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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMD8 All Species: 31.21
Human Site: Y85 Identified Species: 62.42
UniProt: P48556 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48556 NP_002803.2 257 30005 Y85 L K C Y Y F D Y K E Q L P E S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533681 351 39556 Y179 L K C Y Y F D Y K E Q L P E S
Cat Felis silvestris
Mouse Mus musculus Q9CX56 257 30007 Y85 L K C Y Y F D Y K E Q L P E S
Rat Rattus norvegicus NP_001094301 353 39859 Y181 L K C Y Y F D Y K E Q L P E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505290 215 24409 D44 M S R A K P R D L E Q L P E S
Chicken Gallus gallus
Frog Xenopus laevis NP_001084749 271 31208 Y99 L K C Y Y F D Y K D E L P E S
Zebra Danio Brachydanio rerio NP_001002131 267 30996 Y95 L K C Y Y F D Y K D E L P E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648904 264 30206 Y93 L K C Y Y Y D Y A K I I G E S
Honey Bee Apis mellifera XP_625217 266 30388 Y94 L K C Y Y F D Y K S G L M E S
Nematode Worm Caenorhab. elegans Q23449 250 28777 Y79 I N Q M H T Y Y T M A P E N S
Sea Urchin Strong. purpuratus XP_783742 237 27383 D66 Q L K P Y Y F D F R E S M P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32496 274 31901 N92 L K P Y Y F S N N H K L S E S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 72.9 N.A. 97.2 70.8 N.A. 59.5 N.A. 84.8 82 N.A. 49.6 60.1 37.3 56
Protein Similarity: 100 N.A. N.A. 72.9 N.A. 98.4 72.2 N.A. 65.7 N.A. 88.9 89.1 N.A. 70.4 74.4 57.5 76.2
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 40 N.A. 86.6 86.6 N.A. 60 80 13.3 6.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 46.6 N.A. 100 100 N.A. 80 80 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 51.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 9 0 9 0 0 0 0 % A
% Cys: 0 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 67 17 0 17 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 42 25 0 9 84 0 % E
% Phe: 0 0 0 0 0 67 9 0 9 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % G
% His: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % I
% Lys: 0 75 9 0 9 0 0 0 59 9 9 0 0 0 0 % K
% Leu: 75 9 0 0 0 0 0 0 9 0 0 75 0 0 0 % L
% Met: 9 0 0 9 0 0 0 0 0 9 0 0 17 0 0 % M
% Asn: 0 9 0 0 0 0 0 9 9 0 0 0 0 9 0 % N
% Pro: 0 0 9 9 0 9 0 0 0 0 0 9 59 9 0 % P
% Gln: 9 0 9 0 0 0 0 0 0 0 42 0 0 0 0 % Q
% Arg: 0 0 9 0 0 0 9 0 0 9 0 0 0 0 0 % R
% Ser: 0 9 0 0 0 0 9 0 0 9 0 9 9 0 92 % S
% Thr: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 75 84 17 9 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _