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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINB10
All Species:
20.91
Human Site:
Y106
Identified Species:
51.11
UniProt:
P48595
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48595
NP_005015.1
397
45403
Y106
I
L
K
P
N
D
D
Y
L
L
K
T
A
N
A
Chimpanzee
Pan troglodytes
XP_001148652
733
83249
Y442
I
L
K
P
N
D
D
Y
L
L
K
T
A
N
A
Rhesus Macaque
Macaca mulatta
XP_001092087
386
43345
S105
N
K
L
F
G
E
K
S
A
S
F
R
E
E
Y
Dog
Lupus familis
XP_541071
397
44956
Y106
I
N
N
P
S
T
S
Y
V
L
K
T
A
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1K6
397
45097
Y106
I
L
K
P
G
N
S
Y
V
L
K
T
A
N
R
Rat
Rattus norvegicus
Q8K3K4
397
45368
Y106
I
L
K
H
G
N
S
Y
V
L
K
I
A
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514003
515
59038
Y221
V
N
K
S
S
E
V
Y
V
L
E
S
A
N
K
Chicken
Gallus gallus
O73790
410
47365
Y112
F
N
K
P
R
N
N
Y
S
L
R
S
A
N
R
Frog
Xenopus laevis
Q52L45
377
42679
F99
R
L
F
G
E
K
T
F
N
F
L
P
N
F
L
Zebra Danio
Brachydanio rerio
NP_001009892
384
43337
E100
L
A
N
R
L
Y
G
E
Q
T
Y
Q
L
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.4
47.6
79.5
N.A.
75.3
71.2
N.A.
39.8
47.5
46.3
47.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
53.7
68.7
88.4
N.A.
86.6
84.3
N.A.
56.3
67
65.2
67.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
53.3
N.A.
66.6
53.3
N.A.
33.3
40
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
66.6
N.A.
80
66.6
N.A.
73.3
66.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
10
0
0
0
70
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
20
20
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
20
0
10
0
0
10
0
10
10
10
% E
% Phe:
10
0
10
10
0
0
0
10
0
10
10
0
0
10
0
% F
% Gly:
0
0
0
10
30
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% I
% Lys:
0
10
60
0
0
10
10
0
0
0
50
0
0
0
10
% K
% Leu:
10
50
10
0
10
0
0
0
20
70
10
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
30
20
0
20
30
10
0
10
0
0
0
10
70
0
% N
% Pro:
0
0
0
50
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% Q
% Arg:
10
0
0
10
10
0
0
0
0
0
10
10
0
0
40
% R
% Ser:
0
0
0
10
20
0
30
10
10
10
0
20
0
0
0
% S
% Thr:
0
0
0
0
0
10
10
0
0
10
0
40
0
0
0
% T
% Val:
10
0
0
0
0
0
10
0
40
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
70
0
0
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _