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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSS
All Species:
29.7
Human Site:
S126
Identified Species:
54.44
UniProt:
P48637
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48637
NP_000169.1
474
52385
S126
V
F
L
G
L
N
R
S
D
Y
M
F
Q
R
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101751
474
52453
S126
V
F
L
G
L
N
R
S
D
Y
M
F
Q
R
S
Dog
Lupus familis
XP_851615
474
52365
S126
V
F
L
G
L
N
R
S
D
Y
M
F
Q
R
N
Cat
Felis silvestris
Mouse
Mus musculus
P51855
474
52228
S126
V
F
L
G
L
N
R
S
D
Y
M
F
Q
C
G
Rat
Rattus norvegicus
P46413
474
52326
S126
V
F
L
G
L
N
R
S
D
Y
M
F
Q
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425692
476
52443
S128
V
F
L
G
I
N
R
S
D
Y
M
F
D
C
G
Frog
Xenopus laevis
P35668
474
53565
S126
V
F
L
G
I
N
R
S
D
Y
M
F
D
C
R
Zebra Danio
Brachydanio rerio
XP_002666490
475
52892
S126
I
V
V
G
L
N
R
S
D
Y
M
L
D
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728116
491
54619
L131
Q
A
Y
S
I
G
L
L
R
S
D
Y
M
A
H
Honey Bee
Apis mellifera
XP_396065
485
55637
T132
S
D
L
M
L
D
T
T
C
P
E
K
D
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105162
475
52520
R128
N
I
R
L
G
L
H
R
S
D
Y
M
L
D
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46416
539
60252
L191
K
E
D
I
R
L
G
L
H
R
F
D
Y
M
L
Baker's Yeast
Sacchar. cerevisiae
Q08220
491
55797
R128
N
F
R
L
G
I
F
R
S
D
Y
L
I
D
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
91.9
N.A.
88.6
88.1
N.A.
N.A.
66.5
64.1
63.1
N.A.
41.1
39.3
N.A.
N.A.
Protein Similarity:
100
N.A.
98.3
96.6
N.A.
95.1
95.1
N.A.
N.A.
78.3
77.6
77.2
N.A.
60
57.3
N.A.
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
73.3
73.3
60
N.A.
0
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
93.3
N.A.
N.A.
80
80
73.3
N.A.
13.3
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
40.4
N.A.
37.1
34.4
N.A.
Protein Similarity:
N.A.
60.2
N.A.
55.8
56
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
0
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
31
0
% C
% Asp:
0
8
8
0
0
8
0
0
62
16
8
8
31
16
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
62
0
0
0
0
8
0
0
0
8
54
0
0
0
% F
% Gly:
0
0
0
62
16
8
8
0
0
0
0
0
0
0
16
% G
% His:
0
0
0
0
0
0
8
0
8
0
0
0
0
8
8
% H
% Ile:
8
8
0
8
24
8
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
8
% K
% Leu:
0
0
62
16
54
16
8
16
0
0
0
16
8
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
62
8
8
8
0
% M
% Asn:
16
0
0
0
0
62
0
0
0
0
0
0
0
0
16
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
39
0
0
% Q
% Arg:
0
0
16
0
8
0
62
16
8
8
0
0
0
24
8
% R
% Ser:
8
0
0
8
0
0
0
62
16
8
0
0
0
0
39
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% T
% Val:
54
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
62
16
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _