KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSS
All Species:
20.3
Human Site:
S181
Identified Species:
37.22
UniProt:
P48637
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48637
NP_000169.1
474
52385
S181
K
E
A
G
K
I
L
S
N
N
P
S
K
G
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101751
474
52453
S181
K
E
A
G
K
I
L
S
N
N
P
S
K
G
L
Dog
Lupus familis
XP_851615
474
52365
S181
K
E
A
A
K
I
L
S
N
N
P
S
K
G
L
Cat
Felis silvestris
Mouse
Mus musculus
P51855
474
52228
S181
K
E
A
S
K
I
L
S
N
N
P
S
K
G
L
Rat
Rattus norvegicus
P46413
474
52326
S181
N
E
A
S
K
I
L
S
N
N
P
S
K
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425692
476
52443
P183
E
E
A
A
R
L
L
P
N
D
P
A
R
G
L
Frog
Xenopus laevis
P35668
474
53565
T181
E
E
S
S
S
I
L
T
N
D
A
V
E
G
I
Zebra Danio
Brachydanio rerio
XP_002666490
475
52892
D181
D
E
C
S
L
V
L
D
N
N
P
A
A
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728116
491
54619
D186
D
K
L
H
N
M
P
D
N
N
A
L
A
G
L
Honey Bee
Apis mellifera
XP_396065
485
55637
E187
K
E
I
K
N
L
P
E
N
N
A
L
Q
I
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105162
475
52520
A183
L
E
H
K
R
V
P
A
N
A
A
S
T
Q
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46416
539
60252
V246
I
G
I
D
S
E
R
V
P
I
N
T
S
T
I
Baker's Yeast
Sacchar. cerevisiae
Q08220
491
55797
D183
P
K
G
P
I
Y
N
D
Q
N
M
V
I
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
91.9
N.A.
88.6
88.1
N.A.
N.A.
66.5
64.1
63.1
N.A.
41.1
39.3
N.A.
N.A.
Protein Similarity:
100
N.A.
98.3
96.6
N.A.
95.1
95.1
N.A.
N.A.
78.3
77.6
77.2
N.A.
60
57.3
N.A.
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
86.6
N.A.
N.A.
46.6
33.3
46.6
N.A.
26.6
26.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
86.6
N.A.
N.A.
86.6
73.3
60
N.A.
40
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
40.4
N.A.
37.1
34.4
N.A.
Protein Similarity:
N.A.
60.2
N.A.
55.8
56
N.A.
P-Site Identity:
N.A.
20
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
47
16
0
0
0
8
0
8
31
16
16
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
8
0
0
0
24
0
16
0
0
0
0
8
% D
% Glu:
16
77
0
0
0
8
0
8
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
8
16
0
0
0
0
0
0
0
0
0
70
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
16
0
8
47
0
0
0
8
0
0
8
8
24
% I
% Lys:
39
16
0
16
39
0
0
0
0
0
0
0
39
0
0
% K
% Leu:
8
0
8
0
8
16
62
0
0
0
0
16
0
0
62
% L
% Met:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
0
16
0
8
0
85
70
8
0
0
0
0
% N
% Pro:
8
0
0
8
0
0
24
8
8
0
54
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
16
0
8
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
8
31
16
0
0
39
0
0
0
47
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
8
8
8
0
% T
% Val:
0
0
0
0
0
16
0
8
0
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _