KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSS
All Species:
40.91
Human Site:
T299
Identified Species:
75
UniProt:
P48637
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48637
NP_000169.1
474
52385
T299
A
K
C
P
D
I
A
T
Q
L
A
G
T
K
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101751
474
52453
T299
A
K
C
P
D
I
A
T
Q
L
A
G
T
K
K
Dog
Lupus familis
XP_851615
474
52365
T299
V
K
C
P
D
I
A
T
Q
L
A
G
T
K
K
Cat
Felis silvestris
Mouse
Mus musculus
P51855
474
52228
I299
A
K
C
P
D
I
A
I
Q
L
A
G
T
K
K
Rat
Rattus norvegicus
P46413
474
52326
T299
A
K
C
P
D
I
A
T
Q
L
A
G
T
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425692
476
52443
T301
V
K
C
P
D
I
A
T
Q
L
A
G
T
K
K
Frog
Xenopus laevis
P35668
474
53565
T299
V
K
C
P
D
V
P
T
Q
L
V
G
T
K
K
Zebra Danio
Brachydanio rerio
XP_002666490
475
52892
T300
V
K
C
P
D
I
S
T
H
L
A
G
T
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728116
491
54619
Y307
I
K
C
P
S
I
H
Y
H
L
A
G
T
K
K
Honey Bee
Apis mellifera
XP_396065
485
55637
Y308
I
K
C
P
T
I
Q
Y
H
L
A
G
T
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105162
475
52520
Y303
V
K
C
P
S
I
S
Y
H
L
V
G
T
K
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46416
539
60252
Y368
V
K
C
P
S
I
A
Y
H
L
T
G
S
K
K
Baker's Yeast
Sacchar. cerevisiae
Q08220
491
55797
T318
I
K
A
P
D
L
L
T
Q
L
S
G
S
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
91.9
N.A.
88.6
88.1
N.A.
N.A.
66.5
64.1
63.1
N.A.
41.1
39.3
N.A.
N.A.
Protein Similarity:
100
N.A.
98.3
96.6
N.A.
95.1
95.1
N.A.
N.A.
78.3
77.6
77.2
N.A.
60
57.3
N.A.
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
100
N.A.
N.A.
93.3
73.3
80
N.A.
66.6
66.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
100
N.A.
N.A.
93.3
80
86.6
N.A.
66.6
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
40.4
N.A.
37.1
34.4
N.A.
Protein Similarity:
N.A.
60.2
N.A.
55.8
56
N.A.
P-Site Identity:
N.A.
60
N.A.
60
60
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
66.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
8
0
0
0
54
0
0
0
70
0
0
0
0
% A
% Cys:
0
0
93
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
39
0
0
0
0
0
0
% H
% Ile:
24
0
0
0
0
85
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
100
0
0
0
0
0
0
0
0
0
0
0
100
100
% K
% Leu:
0
0
0
0
0
8
8
0
0
100
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
100
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
62
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
24
0
16
0
0
0
8
0
16
0
0
% S
% Thr:
0
0
0
0
8
0
0
62
0
0
8
0
85
0
0
% T
% Val:
47
0
0
0
0
8
0
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _