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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTDSS1
All Species:
28.79
Human Site:
S377
Identified Species:
48.72
UniProt:
P48651
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48651
NP_055569.1
473
55528
S377
K
F
G
Q
D
L
F
S
K
T
Q
I
L
Y
V
Chimpanzee
Pan troglodytes
XP_001145729
327
38255
K232
F
G
Q
D
L
F
S
K
T
Q
I
L
Y
V
V
Rhesus Macaque
Macaca mulatta
XP_001091545
473
55539
S377
K
F
G
Q
D
L
F
S
K
T
Q
I
L
Y
V
Dog
Lupus familis
XP_854779
507
59109
S411
K
F
G
Q
D
L
F
S
K
T
Q
I
L
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99LH2
473
55585
S377
K
F
G
Q
D
L
F
S
K
T
Q
I
L
Y
V
Rat
Rattus norvegicus
NP_001012113
473
55645
S377
K
F
G
Q
D
L
F
S
K
T
Q
I
L
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505556
461
54262
S365
K
F
G
Q
D
L
F
S
K
T
Q
I
L
Y
V
Chicken
Gallus gallus
NP_001026676
473
55473
S377
K
F
G
Q
D
L
F
S
K
T
Q
I
L
Y
V
Frog
Xenopus laevis
NP_001090249
465
54716
I369
F
L
E
A
S
V
C
I
K
F
G
Q
D
L
F
Zebra Danio
Brachydanio rerio
NP_957250
465
54427
K370
L
E
A
L
A
C
I
K
F
G
Q
D
L
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649242
498
56816
T398
Y
Y
V
Y
V
T
D
T
R
C
K
R
V
G
T
Honey Bee
Apis mellifera
XP_393811
477
54933
W379
S
R
V
G
T
Q
C
W
V
Y
G
A
I
M
V
Nematode Worm
Caenorhab. elegans
NP_509673
507
58724
K400
Y
A
T
D
P
L
I
K
R
L
G
M
Q
C
W
Sea Urchin
Strong. purpuratus
XP_001196273
245
28950
V150
Y
A
A
N
C
S
D
V
S
I
E
R
V
W
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.1
99.7
89.3
N.A.
97.2
97
N.A.
80.3
91.7
86
78
N.A.
48.1
48.4
41.4
30.4
Protein Similarity:
100
69.1
99.7
91.5
N.A.
99.3
98.9
N.A.
86.8
96.8
92.1
86.6
N.A.
65.2
66.6
58.7
39.7
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
100
100
6.6
13.3
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
100
13.3
20
N.A.
33.3
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
15
8
8
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
8
8
15
0
0
8
0
0
0
8
0
% C
% Asp:
0
0
0
15
50
0
15
0
0
0
0
8
8
0
0
% D
% Glu:
0
8
8
0
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
15
50
0
0
0
8
50
0
8
8
0
0
0
8
8
% F
% Gly:
0
8
50
8
0
0
0
0
0
8
22
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
15
8
0
8
8
50
8
0
0
% I
% Lys:
50
0
0
0
0
0
0
22
58
0
8
0
0
0
0
% K
% Leu:
8
8
0
8
8
58
0
0
0
8
0
8
58
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
50
0
8
0
0
0
8
58
8
8
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
15
0
0
15
0
0
0
% R
% Ser:
8
0
0
0
8
8
8
50
8
0
0
0
0
0
8
% S
% Thr:
0
0
8
0
8
8
0
8
8
50
0
0
0
0
8
% T
% Val:
0
0
15
0
8
8
0
8
8
0
0
0
15
8
65
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
8
% W
% Tyr:
22
8
0
8
0
0
0
0
0
8
0
0
8
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _