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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTDSS1
All Species:
26.36
Human Site:
S442
Identified Species:
44.62
UniProt:
P48651
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48651
NP_055569.1
473
55528
S442
G
T
K
G
S
E
D
S
P
P
K
H
A
G
N
Chimpanzee
Pan troglodytes
XP_001145729
327
38255
P297
T
K
G
S
E
D
S
P
P
K
H
A
G
N
N
Rhesus Macaque
Macaca mulatta
XP_001091545
473
55539
S442
G
T
K
G
S
E
D
S
P
P
K
H
A
S
N
Dog
Lupus familis
XP_854779
507
59109
S476
G
S
K
G
S
E
D
S
P
P
K
H
P
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q99LH2
473
55585
S442
G
S
K
G
S
E
D
S
P
P
K
H
S
S
N
Rat
Rattus norvegicus
NP_001012113
473
55645
S442
G
S
K
G
S
E
D
S
P
P
K
H
S
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505556
461
54262
S430
F
T
K
G
N
E
D
S
P
P
K
H
S
G
N
Chicken
Gallus gallus
NP_001026676
473
55473
S442
F
S
K
G
A
D
N
S
P
P
K
H
P
V
N
Frog
Xenopus laevis
NP_001090249
465
54716
D434
D
I
P
W
H
H
N
D
K
P
V
E
A
P
I
Zebra Danio
Brachydanio rerio
NP_957250
465
54427
K435
G
D
S
V
T
E
C
K
G
E
F
E
I
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649242
498
56816
L463
V
Y
W
Q
Q
R
Q
L
K
K
V
S
S
T
P
Honey Bee
Apis mellifera
XP_393811
477
54933
C444
K
K
A
T
S
K
Q
C
I
T
Q
L
D
N
S
Nematode Worm
Caenorhab. elegans
NP_509673
507
58724
T465
A
K
R
S
S
A
T
T
E
I
E
I
D
G
E
Sea Urchin
Strong. purpuratus
XP_001196273
245
28950
D215
W
W
D
A
I
I
L
D
V
L
V
C
N
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.1
99.7
89.3
N.A.
97.2
97
N.A.
80.3
91.7
86
78
N.A.
48.1
48.4
41.4
30.4
Protein Similarity:
100
69.1
99.7
91.5
N.A.
99.3
98.9
N.A.
86.8
96.8
92.1
86.6
N.A.
65.2
66.6
58.7
39.7
P-Site Identity:
100
13.3
93.3
86.6
N.A.
80
80
N.A.
80
53.3
13.3
13.3
N.A.
0
6.6
13.3
6.6
P-Site Similarity:
100
20
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
80
20
26.6
N.A.
6.6
26.6
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
8
0
0
0
0
0
8
22
0
0
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% C
% Asp:
8
8
8
0
0
15
43
15
0
0
0
0
15
8
0
% D
% Glu:
0
0
0
0
8
50
0
0
8
8
8
15
0
0
8
% E
% Phe:
15
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
43
0
8
50
0
0
0
0
8
0
0
0
8
36
0
% G
% His:
0
0
0
0
8
8
0
0
0
0
8
50
0
0
0
% H
% Ile:
0
8
0
0
8
8
0
0
8
8
0
8
8
0
8
% I
% Lys:
8
22
50
0
0
8
0
8
15
15
50
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
8
8
0
8
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
15
0
0
0
0
0
8
22
58
% N
% Pro:
0
0
8
0
0
0
0
8
58
58
0
0
15
8
8
% P
% Gln:
0
0
0
8
8
0
15
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
29
8
15
50
0
8
50
0
0
0
8
29
15
15
% S
% Thr:
8
22
0
8
8
0
8
8
0
8
0
0
0
8
0
% T
% Val:
8
0
0
8
0
0
0
0
8
0
22
0
0
8
0
% V
% Trp:
8
8
8
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _