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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTDSS1
All Species:
31.21
Human Site:
S455
Identified Species:
52.82
UniProt:
P48651
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48651
NP_055569.1
473
55528
S455
G
N
N
E
S
H
S
S
R
R
R
N
R
H
S
Chimpanzee
Pan troglodytes
XP_001145729
327
38255
R310
N
N
E
S
H
S
S
R
R
R
N
R
H
S
K
Rhesus Macaque
Macaca mulatta
XP_001091545
473
55539
S455
S
N
N
E
S
H
S
S
R
R
R
N
R
H
S
Dog
Lupus familis
XP_854779
507
59109
S489
G
N
H
E
S
H
S
S
R
R
R
N
R
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99LH2
473
55585
S455
S
N
H
E
S
H
S
S
R
R
R
N
R
H
S
Rat
Rattus norvegicus
NP_001012113
473
55645
S455
N
N
N
E
S
H
S
S
R
R
R
N
R
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505556
461
54262
S443
G
N
S
E
S
H
S
S
R
R
R
N
R
H
S
Chicken
Gallus gallus
NP_001026676
473
55473
S455
V
N
S
E
S
H
S
S
R
R
R
N
R
H
S
Frog
Xenopus laevis
NP_001090249
465
54716
T447
P
I
K
Q
S
E
G
T
S
R
R
K
N
R
H
Zebra Danio
Brachydanio rerio
NP_957250
465
54427
T448
D
S
T
T
S
C
S
T
R
K
R
R
D
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649242
498
56816
T476
T
P
A
K
T
K
E
T
I
P
A
S
S
S
S
Honey Bee
Apis mellifera
XP_393811
477
54933
L457
N
S
H
L
D
V
T
L
S
S
G
D
M
V
H
Nematode Worm
Caenorhab. elegans
NP_509673
507
58724
L478
G
E
N
C
D
I
Y
L
D
S
S
H
E
N
L
Sea Urchin
Strong. purpuratus
XP_001196273
245
28950
M228
G
L
G
I
W
L
G
M
K
L
C
R
R
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.1
99.7
89.3
N.A.
97.2
97
N.A.
80.3
91.7
86
78
N.A.
48.1
48.4
41.4
30.4
Protein Similarity:
100
69.1
99.7
91.5
N.A.
99.3
98.9
N.A.
86.8
96.8
92.1
86.6
N.A.
65.2
66.6
58.7
39.7
P-Site Identity:
100
26.6
93.3
93.3
N.A.
86.6
93.3
N.A.
93.3
86.6
20
26.6
N.A.
6.6
0
13.3
13.3
P-Site Similarity:
100
26.6
93.3
100
N.A.
93.3
93.3
N.A.
100
93.3
33.3
46.6
N.A.
33.3
26.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
8
0
8
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
15
0
0
0
8
0
0
8
8
0
0
% D
% Glu:
0
8
8
50
0
8
8
0
0
0
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
36
0
8
0
0
0
15
0
0
0
8
0
0
0
8
% G
% His:
0
0
22
0
8
50
0
0
0
0
0
8
8
50
15
% H
% Ile:
0
8
0
8
0
8
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
8
0
0
8
8
0
8
0
0
8
% K
% Leu:
0
8
0
8
0
8
0
15
0
8
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
22
58
29
0
0
0
0
0
0
0
8
50
8
8
0
% N
% Pro:
8
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
65
65
65
22
58
8
0
% R
% Ser:
15
15
15
8
65
8
65
50
15
15
8
8
8
22
58
% S
% Thr:
8
0
8
8
8
0
8
22
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _