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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTDSS1
All Species:
26.67
Human Site:
T415
Identified Species:
45.13
UniProt:
P48651
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48651
NP_055569.1
473
55528
T415
H
Y
G
H
R
E
K
T
Y
S
E
C
E
D
G
Chimpanzee
Pan troglodytes
XP_001145729
327
38255
Y270
Y
G
H
R
E
K
T
Y
S
E
C
E
D
G
T
Rhesus Macaque
Macaca mulatta
XP_001091545
473
55539
T415
H
Y
G
H
R
E
K
T
Y
S
E
C
E
D
G
Dog
Lupus familis
XP_854779
507
59109
T449
H
Y
G
H
R
E
K
T
Y
S
E
C
D
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99LH2
473
55585
T415
H
Y
G
H
R
E
K
T
Y
S
E
C
E
D
G
Rat
Rattus norvegicus
NP_001012113
473
55645
T415
H
Y
G
H
R
E
K
T
Y
S
E
C
E
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505556
461
54262
T403
H
C
G
H
R
E
K
T
Y
S
E
C
E
D
S
Chicken
Gallus gallus
NP_001026676
473
55473
T415
Y
Y
G
H
R
E
K
T
L
S
E
S
E
D
S
Frog
Xenopus laevis
NP_001090249
465
54716
D407
Y
G
M
V
W
Y
A
D
Y
C
G
Q
R
E
K
Zebra Danio
Brachydanio rerio
NP_957250
465
54427
N408
V
M
V
W
Y
A
E
N
Y
G
P
R
Q
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649242
498
56816
N436
F
E
R
T
Q
A
I
N
I
V
L
W
L
T
V
Honey Bee
Apis mellifera
XP_393811
477
54933
L417
L
W
L
L
C
Q
S
L
V
S
V
L
C
V
Y
Nematode Worm
Caenorhab. elegans
NP_509673
507
58724
I438
V
A
I
T
P
I
V
I
W
I
L
F
L
I
V
Sea Urchin
Strong. purpuratus
XP_001196273
245
28950
V188
V
L
C
W
I
I
S
V
T
W
E
I
T
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.1
99.7
89.3
N.A.
97.2
97
N.A.
80.3
91.7
86
78
N.A.
48.1
48.4
41.4
30.4
Protein Similarity:
100
69.1
99.7
91.5
N.A.
99.3
98.9
N.A.
86.8
96.8
92.1
86.6
N.A.
65.2
66.6
58.7
39.7
P-Site Identity:
100
0
100
93.3
N.A.
100
100
N.A.
86.6
73.3
6.6
6.6
N.A.
0
6.6
0
6.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
86.6
80
20
20
N.A.
6.6
20
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
15
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
8
8
0
8
0
0
0
0
8
8
43
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
15
50
0
% D
% Glu:
0
8
0
0
8
50
8
0
0
8
58
8
43
15
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
15
50
0
0
0
0
0
0
8
8
0
0
8
36
% G
% His:
43
0
8
50
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
15
8
8
8
8
0
8
0
8
0
% I
% Lys:
0
0
0
0
0
8
50
0
0
0
0
0
0
8
8
% K
% Leu:
8
8
8
8
0
0
0
8
8
0
15
8
15
0
8
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
8
0
0
0
0
0
8
8
0
0
% Q
% Arg:
0
0
8
8
50
0
0
0
0
0
0
8
8
0
0
% R
% Ser:
0
0
0
0
0
0
15
0
8
58
0
8
0
0
22
% S
% Thr:
0
0
0
15
0
0
8
50
8
0
0
0
8
8
8
% T
% Val:
22
0
8
8
0
0
8
8
8
8
8
0
0
8
15
% V
% Trp:
0
8
0
15
8
0
0
0
8
8
0
8
0
0
0
% W
% Tyr:
22
43
0
0
8
8
0
8
58
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _