KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTDSS1
All Species:
25.15
Human Site:
T436
Identified Species:
42.56
UniProt:
P48651
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48651
NP_055569.1
473
55528
T436
S
W
H
H
R
K
G
T
K
G
S
E
D
S
P
Chimpanzee
Pan troglodytes
XP_001145729
327
38255
K291
W
H
H
R
K
G
T
K
G
S
E
D
S
P
P
Rhesus Macaque
Macaca mulatta
XP_001091545
473
55539
T436
S
W
H
H
R
K
G
T
K
G
S
E
D
S
P
Dog
Lupus familis
XP_854779
507
59109
S470
S
W
S
H
A
K
G
S
K
G
S
E
D
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99LH2
473
55585
S436
S
W
H
H
G
K
G
S
K
G
S
E
D
S
P
Rat
Rattus norvegicus
NP_001012113
473
55645
S436
S
W
Y
H
G
K
G
S
K
G
S
E
D
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505556
461
54262
T424
S
W
L
H
S
K
F
T
K
G
N
E
D
S
P
Chicken
Gallus gallus
NP_001026676
473
55473
S436
S
W
L
H
S
K
F
S
K
G
A
D
N
S
P
Frog
Xenopus laevis
NP_001090249
465
54716
I428
D
S
T
Y
N
T
D
I
P
W
H
H
N
D
K
Zebra Danio
Brachydanio rerio
NP_957250
465
54427
D429
S
I
Y
S
E
A
G
D
S
V
T
E
C
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649242
498
56816
Y457
A
F
V
Y
L
A
V
Y
W
Q
Q
R
Q
L
K
Honey Bee
Apis mellifera
XP_393811
477
54933
K438
R
Y
F
E
T
E
K
K
A
T
S
K
Q
C
I
Nematode Worm
Caenorhab. elegans
NP_509673
507
58724
K459
W
F
S
V
W
W
A
K
R
S
S
A
T
T
E
Sea Urchin
Strong. purpuratus
XP_001196273
245
28950
W209
P
N
F
A
E
C
W
W
D
A
I
I
L
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.1
99.7
89.3
N.A.
97.2
97
N.A.
80.3
91.7
86
78
N.A.
48.1
48.4
41.4
30.4
Protein Similarity:
100
69.1
99.7
91.5
N.A.
99.3
98.9
N.A.
86.8
96.8
92.1
86.6
N.A.
65.2
66.6
58.7
39.7
P-Site Identity:
100
13.3
100
80
N.A.
86.6
80
N.A.
73.3
53.3
0
20
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
26.6
100
86.6
N.A.
93.3
93.3
N.A.
80
80
13.3
33.3
N.A.
20
26.6
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
15
8
0
8
8
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% C
% Asp:
8
0
0
0
0
0
8
8
8
0
0
15
43
15
0
% D
% Glu:
0
0
0
8
15
8
0
0
0
0
8
50
0
0
8
% E
% Phe:
0
15
15
0
0
0
15
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
15
8
43
0
8
50
0
0
0
0
8
% G
% His:
0
8
29
50
0
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
0
8
8
0
0
8
% I
% Lys:
0
0
0
0
8
50
8
22
50
0
0
8
0
8
15
% K
% Leu:
0
0
15
0
8
0
0
0
0
0
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
8
0
15
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
0
0
0
0
8
58
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
0
15
0
0
% Q
% Arg:
8
0
0
8
15
0
0
0
8
0
0
8
0
0
0
% R
% Ser:
58
8
15
8
15
0
0
29
8
15
50
0
8
50
0
% S
% Thr:
0
0
8
0
8
8
8
22
0
8
8
0
8
8
0
% T
% Val:
0
0
8
8
0
0
8
0
0
8
0
0
0
0
8
% V
% Trp:
15
50
0
0
8
8
8
8
8
8
0
0
0
0
0
% W
% Tyr:
0
8
15
15
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _