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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTDSS1
All Species:
26.97
Human Site:
Y424
Identified Species:
45.64
UniProt:
P48651
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48651
NP_055569.1
473
55528
Y424
S
E
C
E
D
G
T
Y
S
P
E
I
S
W
H
Chimpanzee
Pan troglodytes
XP_001145729
327
38255
S279
E
C
E
D
G
T
Y
S
P
E
I
S
W
H
H
Rhesus Macaque
Macaca mulatta
XP_001091545
473
55539
Y424
S
E
C
E
D
G
T
Y
S
P
E
I
S
W
H
Dog
Lupus familis
XP_854779
507
59109
Y458
S
E
C
D
D
G
T
Y
G
P
E
I
S
W
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99LH2
473
55585
Y424
S
E
C
E
D
G
T
Y
S
P
E
I
S
W
H
Rat
Rattus norvegicus
NP_001012113
473
55645
Y424
S
E
C
E
D
G
T
Y
S
P
E
I
S
W
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505556
461
54262
Y412
S
E
C
E
D
S
T
Y
S
P
D
V
S
W
L
Chicken
Gallus gallus
NP_001026676
473
55473
Y424
S
E
S
E
D
S
P
Y
S
P
D
A
S
W
L
Frog
Xenopus laevis
NP_001090249
465
54716
F416
C
G
Q
R
E
K
T
F
S
E
C
E
D
S
T
Zebra Danio
Brachydanio rerio
NP_957250
465
54427
S417
G
P
R
Q
K
S
F
S
E
C
E
D
S
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649242
498
56816
V445
V
L
W
L
T
V
Q
V
I
I
S
V
A
F
V
Honey Bee
Apis mellifera
XP_393811
477
54933
C426
S
V
L
C
V
Y
G
C
V
L
W
H
R
Y
F
Nematode Worm
Caenorhab. elegans
NP_509673
507
58724
T447
I
L
F
L
I
V
G
T
F
F
S
V
W
F
S
Sea Urchin
Strong. purpuratus
XP_001196273
245
28950
F197
W
E
I
T
E
L
F
F
I
H
I
Q
P
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.1
99.7
89.3
N.A.
97.2
97
N.A.
80.3
91.7
86
78
N.A.
48.1
48.4
41.4
30.4
Protein Similarity:
100
69.1
99.7
91.5
N.A.
99.3
98.9
N.A.
86.8
96.8
92.1
86.6
N.A.
65.2
66.6
58.7
39.7
P-Site Identity:
100
6.6
100
80
N.A.
100
93.3
N.A.
73.3
60
13.3
13.3
N.A.
0
6.6
0
6.6
P-Site Similarity:
100
13.3
100
86.6
N.A.
100
100
N.A.
86.6
66.6
26.6
26.6
N.A.
20
13.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% A
% Cys:
8
8
43
8
0
0
0
8
0
8
8
0
0
0
0
% C
% Asp:
0
0
0
15
50
0
0
0
0
0
15
8
8
0
0
% D
% Glu:
8
58
8
43
15
0
0
0
8
15
43
8
0
0
0
% E
% Phe:
0
0
8
0
0
0
15
15
8
8
0
0
0
15
15
% F
% Gly:
8
8
0
0
8
36
15
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
29
% H
% Ile:
8
0
8
0
8
0
0
0
15
8
15
36
0
8
0
% I
% Lys:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
15
8
15
0
8
0
0
0
8
0
0
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
8
0
8
50
0
0
8
0
0
% P
% Gln:
0
0
8
8
0
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
8
8
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
58
0
8
0
0
22
0
15
50
0
15
8
58
8
15
% S
% Thr:
0
0
0
8
8
8
50
8
0
0
0
0
0
0
8
% T
% Val:
8
8
0
0
8
15
0
8
8
0
0
22
0
0
8
% V
% Trp:
8
0
8
0
0
0
0
0
0
0
8
0
15
50
0
% W
% Tyr:
0
0
0
0
0
8
8
50
0
0
0
0
0
8
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _