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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KRT6C All Species: 4.24
Human Site: S76 Identified Species: 13.33
UniProt: P48668 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48668 NP_775109.2 564 60025 S76 R I S I G G G S C A I S G G Y
Chimpanzee Pan troglodytes A5A6M8 592 62520 G80 W I S I S T S G G S F R N R F
Rhesus Macaque Macaca mulatta XP_001095535 564 59948 S76 R I S I G G G S C A I G G G Y
Dog Lupus familis XP_850008 570 60565 A96 G F A Y G G G A A S G F G F G
Cat Felis silvestris
Mouse Mus musculus Q9Z331 562 60304 G82 C G I G G G Y G S R F G G A Y
Rat Rattus norvegicus Q4FZU2 552 59231 R84 I G G G Y G G R F G G S F G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514525 557 59427 G80 R I S I S A G G C Y G G R G G
Chicken Gallus gallus O93532 492 53785 G77 G Y G G M G F G G A I A P S A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.1 98.2 88.4 N.A. 85.1 82 N.A. 80.3 64.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 82.9 99.4 92.6 N.A. 91.3 88.4 N.A. 85.9 74.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 93.3 26.6 N.A. 26.6 33.3 N.A. 46.6 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 93.3 46.6 N.A. 26.6 33.3 N.A. 46.6 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 0 13 0 13 13 38 0 13 0 13 13 % A
% Cys: 13 0 0 0 0 0 0 0 38 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 13 0 0 0 0 13 0 13 0 25 13 13 13 13 % F
% Gly: 25 25 25 38 50 75 63 50 25 13 38 38 50 50 25 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 13 50 13 50 0 0 0 0 0 0 38 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 38 0 0 0 0 0 0 13 0 13 0 13 13 13 0 % R
% Ser: 0 0 50 0 25 0 13 25 13 25 0 25 0 13 0 % S
% Thr: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 13 0 13 13 0 13 0 0 13 0 0 0 0 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _