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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NES
All Species:
13.94
Human Site:
S659
Identified Species:
38.33
UniProt:
P48681
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48681
NP_006608.1
1621
177439
S659
E
N
Q
E
L
V
S
S
L
Q
E
N
L
E
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116693
1619
177293
S659
E
N
Q
E
L
V
S
S
L
Q
E
N
L
E
S
Dog
Lupus familis
XP_547531
1720
190097
S667
E
N
Q
E
L
V
R
S
L
E
E
N
F
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5H2
1864
207106
S688
E
D
Q
R
F
P
R
S
P
E
E
D
Q
Q
A
Rat
Rattus norvegicus
P21263
1893
208779
P730
S
Q
E
S
L
R
S
P
E
E
E
D
Q
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518179
1378
147909
A511
E
K
A
D
P
R
A
A
G
T
K
N
E
E
A
Chicken
Gallus gallus
NP_990364
1840
202262
E712
T
G
R
A
R
D
D
E
G
E
E
E
D
K
G
Frog
Xenopus laevis
Q01550
1744
199544
T704
K
L
F
E
N
K
S
T
E
D
Q
L
I
T
N
Zebra Danio
Brachydanio rerio
XP_001919922
1265
143381
T402
P
P
S
S
T
S
M
T
E
K
T
E
D
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
92.5
57.9
N.A.
50.3
50.1
N.A.
23
26.7
22.3
21.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
94.6
68.9
N.A.
61.5
61.1
N.A.
38.3
42.5
40.5
40.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
80
N.A.
26.6
26.6
N.A.
20
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
86.6
N.A.
60
53.3
N.A.
53.3
26.6
46.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
0
0
12
12
0
0
0
0
0
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
12
0
12
12
0
0
12
0
23
23
0
0
% D
% Glu:
56
0
12
45
0
0
0
12
34
45
67
23
12
56
0
% E
% Phe:
0
0
12
0
12
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
12
0
0
0
0
0
0
23
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% I
% Lys:
12
12
0
0
0
12
0
0
0
12
12
0
0
12
0
% K
% Leu:
0
12
0
0
45
0
0
0
34
0
0
12
23
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
34
0
0
12
0
0
0
0
0
0
45
0
0
12
% N
% Pro:
12
12
0
0
12
12
0
12
12
0
0
0
0
0
0
% P
% Gln:
0
12
45
0
0
0
0
0
0
23
12
0
23
12
0
% Q
% Arg:
0
0
12
12
12
23
23
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
12
23
0
12
45
45
0
0
0
0
0
0
34
% S
% Thr:
12
0
0
0
12
0
0
23
0
12
12
0
0
12
0
% T
% Val:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _