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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMT All Species: 25.45
Human Site: S287 Identified Species: 37.33
UniProt: P48728 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48728 NP_000472.2 403 43946 S287 H T T P V E G S L S W T L G K
Chimpanzee Pan troglodytes XP_517018 403 43880 S287 H T T P V E G S L S W T L G K
Rhesus Macaque Macaca mulatta XP_001108852 403 43940 S287 H T T P V E G S L S W T L G K
Dog Lupus familis XP_542460 340 36269 L253 P A A A A V H L A A A L L E N
Cat Felis silvestris
Mouse Mus musculus Q8CFA2 403 43990 S287 H T T P V E G S L S W T L G K
Rat Rattus norvegicus NP_001014026 403 44045 S287 H T T P V E G S L S W T L G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515256 343 36787 Q251 G A A V I V P Q I K G K L K R
Chicken Gallus gallus P28337 392 42040 G276 S T T P V E A G L L W T L G K
Frog Xenopus laevis NP_001090416 404 44196 S288 T T T P V E A S L V W T L G K
Zebra Danio Brachydanio rerio NP_001006021 409 44724 T294 T T T P V E A T L V W T I G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_504502 402 43902 G283 N T T P I E A G L A F V V A K
Sea Urchin Strong. purpuratus XP_785085 391 42421 M273 D T T P V E A M L G W T I G K
Poplar Tree Populus trichocarpa XP_002316546 408 44235 G292 H I T P V E A G L N W A I G K
Maize Zea mays NP_001145825 409 44016 G293 H I T P V E A G L S W A I G K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65396 408 44426 G292 H I S P V E A G L T W A I G K
Baker's Yeast Sacchar. cerevisiae P48015 400 44451 A276 S I T P V E A A L N W V I S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.2 63.2 N.A. 88.8 88.8 N.A. 67.2 65.2 68 64.3 N.A. N.A. N.A. 52.3 56.3
Protein Similarity: 100 99.7 98.2 68.9 N.A. 93 92.5 N.A. 75.1 74.4 77.7 76.5 N.A. N.A. N.A. 67.7 69.9
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 6.6 73.3 80 66.6 N.A. N.A. N.A. 40 66.6
P-Site Similarity: 100 100 100 13.3 N.A. 100 100 N.A. 26.6 73.3 80 80 N.A. N.A. N.A. 73.3 73.3
Percent
Protein Identity: 48.7 51.5 N.A. 48.7 40.4 N.A.
Protein Similarity: 64.9 65.7 N.A. 66.1 58.5 N.A.
P-Site Identity: 60 66.6 N.A. 53.3 46.6 N.A.
P-Site Similarity: 73.3 73.3 N.A. 73.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 13 7 7 0 57 7 7 13 7 19 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 88 0 0 0 0 0 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 7 0 0 0 0 0 32 32 0 7 7 0 0 75 0 % G
% His: 50 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 25 0 0 13 0 0 0 7 0 0 0 38 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 7 0 7 0 7 88 % K
% Leu: 0 0 0 0 0 0 0 7 88 7 0 7 57 0 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 13 0 0 0 0 7 % N
% Pro: 7 0 0 88 0 0 7 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % R
% Ser: 13 0 7 0 0 0 0 38 0 38 0 0 0 7 0 % S
% Thr: 13 63 82 0 0 0 0 7 0 7 0 57 0 0 0 % T
% Val: 0 0 0 7 82 13 0 0 0 13 0 13 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 82 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _