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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMT All Species: 35.76
Human Site: S334 Identified Species: 52.44
UniProt: P48728 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48728 NP_000472.2 403 43946 S334 G A P M R A H S P I L N M E G
Chimpanzee Pan troglodytes XP_517018 403 43880 S334 G A P M R A H S P I L N M E G
Rhesus Macaque Macaca mulatta XP_001108852 403 43940 S334 G A P M R A H S P I L N M E G
Dog Lupus familis XP_542460 340 36269 D272 L A G L A A R D S L R L E A G
Cat Felis silvestris
Mouse Mus musculus Q8CFA2 403 43990 S334 G A P V R A H S P I L N T E G
Rat Rattus norvegicus NP_001014026 403 44045 S334 G A P M R A H S P I L N T E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515256 343 36787 S274 G A P V R Q H S P I L N A E G
Chicken Gallus gallus P28337 392 42040 A323 G P P L R P P A A I L G P E G
Frog Xenopus laevis NP_001090416 404 44196 A335 G P P V R Q H A P I L N L E G
Zebra Danio Brachydanio rerio NP_001006021 409 44724 T341 G P P V R Q H T P I L S S D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_504502 402 43902 P333 R C P R S H L P L I D P L D K
Sea Urchin Strong. purpuratus XP_785085 391 42421 S322 P I R G E F N S E I L S N S G
Poplar Tree Populus trichocarpa XP_002316546 408 44235 S339 G P P P R S H S E I Q D E K G
Maize Zea mays NP_001145825 409 44016 S340 G P P A R S H S E L V S G S G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65396 408 44426 S339 G P P A R S H S E V H D E S G
Baker's Yeast Sacchar. cerevisiae P48015 400 44451 I332 A A R N G V K I F L P D A E T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.2 63.2 N.A. 88.8 88.8 N.A. 67.2 65.2 68 64.3 N.A. N.A. N.A. 52.3 56.3
Protein Similarity: 100 99.7 98.2 68.9 N.A. 93 92.5 N.A. 75.1 74.4 77.7 76.5 N.A. N.A. N.A. 67.7 69.9
P-Site Identity: 100 100 100 20 N.A. 86.6 93.3 N.A. 80 46.6 66.6 53.3 N.A. N.A. N.A. 13.3 26.6
P-Site Similarity: 100 100 100 33.3 N.A. 93.3 93.3 N.A. 86.6 60 86.6 80 N.A. N.A. N.A. 26.6 40
Percent
Protein Identity: 48.7 51.5 N.A. 48.7 40.4 N.A.
Protein Similarity: 64.9 65.7 N.A. 66.1 58.5 N.A.
P-Site Identity: 46.6 40 N.A. 40 13.3 N.A.
P-Site Similarity: 66.6 66.6 N.A. 60 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 50 0 13 7 38 0 13 7 0 0 0 13 7 0 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 0 7 19 0 13 0 % D
% Glu: 0 0 0 0 7 0 0 0 25 0 0 0 19 57 0 % E
% Phe: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % F
% Gly: 75 0 7 7 7 0 0 0 0 0 0 7 7 0 88 % G
% His: 0 0 0 0 0 7 69 0 0 0 7 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 7 0 75 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 7 % K
% Leu: 7 0 0 13 0 0 7 0 7 19 63 7 13 0 0 % L
% Met: 0 0 0 25 0 0 0 0 0 0 0 0 19 0 0 % M
% Asn: 0 0 0 7 0 0 7 0 0 0 0 44 7 0 0 % N
% Pro: 7 38 82 7 0 7 7 7 50 0 7 7 7 0 0 % P
% Gln: 0 0 0 0 0 19 0 0 0 0 7 0 0 0 0 % Q
% Arg: 7 0 13 7 75 0 7 0 0 0 7 0 0 0 0 % R
% Ser: 0 0 0 0 7 19 0 63 7 0 0 19 7 19 0 % S
% Thr: 0 0 0 0 0 0 0 7 0 0 0 0 13 0 7 % T
% Val: 0 0 0 25 0 7 0 0 0 7 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _