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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMT All Species: 53.94
Human Site: S353 Identified Species: 79.11
UniProt: P48728 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48728 NP_000472.2 403 43946 S353 T V T S G C P S P S L K K N V
Chimpanzee Pan troglodytes XP_517018 403 43880 S353 T V T S G C P S P S L K K N V
Rhesus Macaque Macaca mulatta XP_001108852 403 43940 S353 T V T S G C P S P S L K K N V
Dog Lupus familis XP_542460 340 36269 T291 G S D I D E H T T P V E G S L
Cat Felis silvestris
Mouse Mus musculus Q8CFA2 403 43990 S353 T V T S G C P S P S L K K N V
Rat Rattus norvegicus NP_001014026 403 44045 S353 T V T S G C P S P S L K K N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515256 343 36787 S293 A V T S G C P S P C L K K N V
Chicken Gallus gallus P28337 392 42040 S342 T V T S G C P S P S L G K N I
Frog Xenopus laevis NP_001090416 404 44196 S354 E V T S G C P S P S L R V N V
Zebra Danio Brachydanio rerio NP_001006021 409 44724 S360 E V T S G C P S P C L K Q N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_504502 402 43902 S352 F V T S G C P S P T L G K N I
Sea Urchin Strong. purpuratus XP_785085 391 42421 S341 D V T S G C P S P S L K N N V
Poplar Tree Populus trichocarpa XP_002316546 408 44235 S358 E I T S G G F S P C L K K N I
Maize Zea mays NP_001145825 409 44016 S359 E V T S G G F S P C L K K N I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65396 408 44426 S358 E I T S G G F S P N L K K N I
Baker's Yeast Sacchar. cerevisiae P48015 400 44451 P351 V T S G S A S P T L N N I N I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.2 63.2 N.A. 88.8 88.8 N.A. 67.2 65.2 68 64.3 N.A. N.A. N.A. 52.3 56.3
Protein Similarity: 100 99.7 98.2 68.9 N.A. 93 92.5 N.A. 75.1 74.4 77.7 76.5 N.A. N.A. N.A. 67.7 69.9
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 86.6 86.6 80 80 N.A. N.A. N.A. 73.3 86.6
P-Site Similarity: 100 100 100 33.3 N.A. 100 100 N.A. 86.6 93.3 86.6 86.6 N.A. N.A. N.A. 86.6 86.6
Percent
Protein Identity: 48.7 51.5 N.A. 48.7 40.4 N.A.
Protein Similarity: 64.9 65.7 N.A. 66.1 58.5 N.A.
P-Site Identity: 60 66.6 N.A. 60 6.6 N.A.
P-Site Similarity: 73.3 73.3 N.A. 80 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 69 0 0 0 25 0 0 0 0 0 % C
% Asp: 7 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 32 0 0 0 0 7 0 0 0 0 0 7 0 0 0 % E
% Phe: 7 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 7 88 19 0 0 0 0 0 13 7 0 0 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 13 0 7 0 0 0 0 0 0 0 0 7 0 38 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 69 69 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 7 88 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 7 7 7 94 0 % N
% Pro: 0 0 0 0 0 0 69 7 88 7 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % R
% Ser: 0 7 7 88 7 0 7 88 0 50 0 0 0 7 0 % S
% Thr: 38 7 88 0 0 0 0 7 13 7 0 0 0 0 0 % T
% Val: 7 75 0 0 0 0 0 0 0 0 7 0 7 0 57 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _