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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMT All Species: 31.52
Human Site: T291 Identified Species: 46.22
UniProt: P48728 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48728 NP_000472.2 403 43946 T291 V E G S L S W T L G K R R R A
Chimpanzee Pan troglodytes XP_517018 403 43880 T291 V E G S L S W T L G K R R R A
Rhesus Macaque Macaca mulatta XP_001108852 403 43940 T291 V E G S L S W T L G K R R R A
Dog Lupus familis XP_542460 340 36269 L257 A V H L A A A L L E N P E V K
Cat Felis silvestris
Mouse Mus musculus Q8CFA2 403 43990 T291 V E G S L S W T L G K R R R I
Rat Rattus norvegicus NP_001014026 403 44045 T291 V E G S L S W T L G K R R R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515256 343 36787 K255 I V P Q I K G K L K R K R V G
Chicken Gallus gallus P28337 392 42040 T280 V E A G L L W T L G K R R R T
Frog Xenopus laevis NP_001090416 404 44196 T292 V E A S L V W T L G K R R R T
Zebra Danio Brachydanio rerio NP_001006021 409 44724 T298 V E A T L V W T I G K R R R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_504502 402 43902 V287 I E A G L A F V V A K R R R E
Sea Urchin Strong. purpuratus XP_785085 391 42421 T277 V E A M L G W T I G K R R R Q
Poplar Tree Populus trichocarpa XP_002316546 408 44235 A296 V E A G L N W A I G K R R K A
Maize Zea mays NP_001145825 409 44016 A297 V E A G L S W A I G K R R R A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65396 408 44426 A296 V E A G L T W A I G K R R R A
Baker's Yeast Sacchar. cerevisiae P48015 400 44451 V280 V E A A L N W V I S K S R R D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.2 63.2 N.A. 88.8 88.8 N.A. 67.2 65.2 68 64.3 N.A. N.A. N.A. 52.3 56.3
Protein Similarity: 100 99.7 98.2 68.9 N.A. 93 92.5 N.A. 75.1 74.4 77.7 76.5 N.A. N.A. N.A. 67.7 69.9
P-Site Identity: 100 100 100 6.6 N.A. 93.3 93.3 N.A. 13.3 73.3 80 66.6 N.A. N.A. N.A. 40 66.6
P-Site Similarity: 100 100 100 13.3 N.A. 93.3 93.3 N.A. 40 73.3 80 80 N.A. N.A. N.A. 66.6 73.3
Percent
Protein Identity: 48.7 51.5 N.A. 48.7 40.4 N.A.
Protein Similarity: 64.9 65.7 N.A. 66.1 58.5 N.A.
P-Site Identity: 60 73.3 N.A. 66.6 46.6 N.A.
P-Site Similarity: 80 80 N.A. 80 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 57 7 7 13 7 19 0 7 0 0 0 0 38 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % D
% Glu: 0 88 0 0 0 0 0 0 0 7 0 0 7 0 7 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 32 32 0 7 7 0 0 75 0 0 0 0 7 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 13 0 0 0 7 0 0 0 38 0 0 0 0 0 7 % I
% Lys: 0 0 0 0 0 7 0 7 0 7 88 7 0 7 7 % K
% Leu: 0 0 0 7 88 7 0 7 57 0 0 0 0 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 13 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 13 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 7 82 94 82 0 % R
% Ser: 0 0 0 38 0 38 0 0 0 7 0 7 0 0 0 % S
% Thr: 0 0 0 7 0 7 0 57 0 0 0 0 0 0 13 % T
% Val: 82 13 0 0 0 13 0 13 7 0 0 0 0 13 7 % V
% Trp: 0 0 0 0 0 0 82 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _