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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMT All Species: 36.06
Human Site: Y141 Identified Species: 52.89
UniProt: P48728 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48728 NP_000472.2 403 43946 Y141 N T S E G H L Y V V S N A G C
Chimpanzee Pan troglodytes XP_517018 403 43880 Y141 N T S E G H L Y V V S N A G C
Rhesus Macaque Macaca mulatta XP_001108852 403 43940 Y141 N T S E G H L Y V V S N A G C
Dog Lupus familis XP_542460 340 36269 D138 N K A G G I K D D L I V T S A
Cat Felis silvestris
Mouse Mus musculus Q8CFA2 403 43990 Y141 N T S E G H L Y V V S N A G C
Rat Rattus norvegicus NP_001014026 403 44045 Y141 N T S E G H L Y V V S N A G C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515256 343 36787 D137 V L Q A G V S D D L R K L P F
Chicken Gallus gallus P28337 392 42040 A143 G C A D K D R A V M E G R A A
Frog Xenopus laevis NP_001090416 404 44196 Y142 K T S D G Y L Y V V S N A G C
Zebra Danio Brachydanio rerio NP_001006021 409 44724 Y148 K T D Q D Y L Y V V S N A G C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_504502 402 43902 F134 K T D K D F L F L V T N A G C
Sea Urchin Strong. purpuratus XP_785085 391 42421 L145 H I K N K L A L F V A E G H D
Poplar Tree Populus trichocarpa XP_002316546 408 44235 Y144 K V T D D H M Y I V V N A G C
Maize Zea mays NP_001145825 409 44016 Y145 K V T D H H I Y L V V N A G C
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65396 408 44426 Y144 K V T D E H I Y L V V N A G C
Baker's Yeast Sacchar. cerevisiae P48015 400 44451 E135 V T N A G C A E R D T E F F H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.2 63.2 N.A. 88.8 88.8 N.A. 67.2 65.2 68 64.3 N.A. N.A. N.A. 52.3 56.3
Protein Similarity: 100 99.7 98.2 68.9 N.A. 93 92.5 N.A. 75.1 74.4 77.7 76.5 N.A. N.A. N.A. 67.7 69.9
P-Site Identity: 100 100 100 13.3 N.A. 100 100 N.A. 6.6 6.6 80 66.6 N.A. N.A. N.A. 46.6 6.6
P-Site Similarity: 100 100 100 26.6 N.A. 100 100 N.A. 13.3 26.6 93.3 80 N.A. N.A. N.A. 73.3 20
Percent
Protein Identity: 48.7 51.5 N.A. 48.7 40.4 N.A.
Protein Similarity: 64.9 65.7 N.A. 66.1 58.5 N.A.
P-Site Identity: 46.6 46.6 N.A. 46.6 13.3 N.A.
P-Site Similarity: 73.3 73.3 N.A. 73.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 13 0 0 13 7 0 0 7 0 69 7 13 % A
% Cys: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 69 % C
% Asp: 0 0 13 32 19 7 0 13 13 7 0 0 0 0 7 % D
% Glu: 0 0 0 32 7 0 0 7 0 0 7 13 0 0 0 % E
% Phe: 0 0 0 0 0 7 0 7 7 0 0 0 7 7 7 % F
% Gly: 7 0 0 7 57 0 0 0 0 0 0 7 7 69 0 % G
% His: 7 0 0 0 7 50 0 0 0 0 0 0 0 7 7 % H
% Ile: 0 7 0 0 0 7 13 0 7 0 7 0 0 0 0 % I
% Lys: 38 7 7 7 13 0 7 0 0 0 0 7 0 0 0 % K
% Leu: 0 7 0 0 0 7 50 7 19 13 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 0 % M
% Asn: 38 0 7 7 0 0 0 0 0 0 0 69 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % P
% Gln: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 7 0 7 0 7 0 7 0 0 % R
% Ser: 0 0 38 0 0 0 7 0 0 0 44 0 0 7 0 % S
% Thr: 0 57 19 0 0 0 0 0 0 0 13 0 7 0 0 % T
% Val: 13 19 0 0 0 7 0 0 50 75 19 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 0 63 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _