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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMT All Species: 22.12
Human Site: Y369 Identified Species: 32.44
UniProt: P48728 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48728 NP_000472.2 403 43946 Y369 M G Y V P C E Y S R P G T M L
Chimpanzee Pan troglodytes XP_517018 403 43880 Y369 M G Y V P C E Y S R P G T M L
Rhesus Macaque Macaca mulatta XP_001108852 403 43940 Y369 M G Y V P C E Y S R P G T M L
Dog Lupus familis XP_542460 340 36269 Q307 W T L G K R H Q A A M D F P G
Cat Felis silvestris
Mouse Mus musculus Q8CFA2 403 43990 Y369 M G Y V P F K Y S R P G T Q L
Rat Rattus norvegicus NP_001014026 403 44045 Y369 M G Y V A F K Y S R P G T Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515256 343 36787 H309 M G Y V D G D H S K P G T P L
Chicken Gallus gallus P28337 392 42040 H358 M G Y V Q A A H S R P G T T L
Frog Xenopus laevis NP_001090416 404 44196 Y370 M G Y V E P E Y A K A G T A V
Zebra Danio Brachydanio rerio NP_001006021 409 44724 F376 M G Y V E T A F S K A G T S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_504502 402 43902 H368 I A Y V D K S H S K I G T K F
Sea Urchin Strong. purpuratus XP_785085 391 42421 H357 M G Y V S A A H A K N G T K V
Poplar Tree Populus trichocarpa XP_002316546 408 44235 F374 M G Y V K S G F H K A G T K A
Maize Zea mays NP_001145825 409 44016 M375 M G Y V K S G M H K A G T E L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65396 408 44426 Q374 M G Y V K S G Q H K T G T K V
Baker's Yeast Sacchar. cerevisiae P48015 400 44451 Y367 Q A Y V Q K G Y H K K G T K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.2 63.2 N.A. 88.8 88.8 N.A. 67.2 65.2 68 64.3 N.A. N.A. N.A. 52.3 56.3
Protein Similarity: 100 99.7 98.2 68.9 N.A. 93 92.5 N.A. 75.1 74.4 77.7 76.5 N.A. N.A. N.A. 67.7 69.9
P-Site Identity: 100 100 100 0 N.A. 80 73.3 N.A. 60 66.6 53.3 46.6 N.A. N.A. N.A. 33.3 40
P-Site Similarity: 100 100 100 6.6 N.A. 86.6 80 N.A. 80 73.3 73.3 66.6 N.A. N.A. N.A. 53.3 66.6
Percent
Protein Identity: 48.7 51.5 N.A. 48.7 40.4 N.A.
Protein Similarity: 64.9 65.7 N.A. 66.1 58.5 N.A.
P-Site Identity: 40 46.6 N.A. 40 40 N.A.
P-Site Similarity: 53.3 53.3 N.A. 53.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 7 13 19 0 19 7 25 0 0 7 7 % A
% Cys: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 13 0 7 0 0 0 0 7 0 0 0 % D
% Glu: 0 0 0 0 13 0 25 0 0 0 0 0 0 7 0 % E
% Phe: 0 0 0 0 0 13 0 13 0 0 0 0 7 0 7 % F
% Gly: 0 82 0 7 0 7 25 0 0 0 0 94 0 0 7 % G
% His: 0 0 0 0 0 0 7 25 25 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 0 7 0 0 0 7 % I
% Lys: 0 0 0 0 25 13 13 0 0 57 7 0 0 32 0 % K
% Leu: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 57 % L
% Met: 82 0 0 0 0 0 0 7 0 0 7 0 0 19 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 0 0 25 7 0 0 0 0 44 0 0 13 0 % P
% Gln: 7 0 0 0 13 0 0 13 0 0 0 0 0 13 0 % Q
% Arg: 0 0 0 0 0 7 0 0 0 38 0 0 0 0 0 % R
% Ser: 0 0 0 0 7 19 7 0 57 0 0 0 0 7 0 % S
% Thr: 0 7 0 0 0 7 0 0 0 0 7 0 94 7 0 % T
% Val: 0 0 0 94 0 0 0 0 0 0 0 0 0 0 19 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 94 0 0 0 0 44 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _