Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK1A1 All Species: 37.58
Human Site: Y294 Identified Species: 59.05
UniProt: P48729 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48729 NP_001020276.1 337 38915 Y294 T L N H Q Y D Y T F D W T M L
Chimpanzee Pan troglodytes XP_001163892 341 39357 Y298 T L N H Q Y D Y T F D W T M L
Rhesus Macaque Macaca mulatta XP_001106705 339 39093 Y296 T L N H Q Y D Y T F D W T M L
Dog Lupus familis XP_867638 336 38749 Y294 T L N H Q Y D Y T F D W T M L
Cat Felis silvestris
Mouse Mus musculus Q9JMK2 416 47304 Y286 R Q G F S Y D Y V F D W N M L
Rat Rattus norvegicus P97633 325 37477 R282 M Y L R Q L F R I L F R T L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P67962 337 38882 Y294 T L N H Q Y D Y T F D W T M L
Frog Xenopus laevis Q5BP74 415 47421 Y286 R Q G F S Y D Y V F D W N M L
Zebra Danio Brachydanio rerio Q7T2E3 403 46225 Y286 R Q G F S Y D Y V F D W N M L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54367 337 39516 H293 I L F R T L N H Q Y D Y I Y D
Honey Bee Apis mellifera XP_393612 350 40282 Y298 T L N H Q Y D Y T F D W T M L
Nematode Worm Caenorhab. elegans P42168 341 39018 Y293 T L N H Q Y D Y T F D W T M L
Sea Urchin Strong. purpuratus XP_786391 348 40003 H304 I L F R T L N H Q Y D F T F D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42158 450 50928 Y286 R E G F Q F D Y V F D W T I L
Baker's Yeast Sacchar. cerevisiae P29295 494 57322 H286 K L E Y H N D H L F D W T M L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 97.6 99.6 N.A. 57.2 96.1 N.A. N.A. 99.6 57.5 59.5 N.A. 74.1 80.8 81.2 78.7
Protein Similarity: 100 98.8 98.2 99.6 N.A. 67.7 96.1 N.A. N.A. 100 67.9 70.2 N.A. 82.7 86.8 86.8 87.3
P-Site Identity: 100 100 100 100 N.A. 53.3 13.3 N.A. N.A. 100 53.3 53.3 N.A. 13.3 100 100 20
P-Site Similarity: 100 100 100 100 N.A. 53.3 20 N.A. N.A. 100 53.3 53.3 N.A. 40 100 100 46.6
Percent
Protein Identity: N.A. N.A. N.A. 50.2 41.9 N.A.
Protein Similarity: N.A. N.A. N.A. 63.1 54.6 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 80 0 0 0 94 0 0 0 14 % D
% Glu: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 14 27 0 7 7 0 0 80 7 7 0 7 0 % F
% Gly: 0 0 27 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 47 7 0 0 20 0 0 0 0 0 0 0 % H
% Ile: 14 0 0 0 0 0 0 0 7 0 0 0 7 7 0 % I
% Lys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 67 7 0 0 20 0 0 7 7 0 0 0 7 80 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 74 0 % M
% Asn: 0 0 47 0 0 7 14 0 0 0 0 0 20 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 20 0 0 60 0 0 0 14 0 0 0 0 0 0 % Q
% Arg: 27 0 0 20 0 0 0 7 0 0 0 7 0 0 0 % R
% Ser: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 47 0 0 0 14 0 0 0 47 0 0 0 74 0 0 % T
% Val: 0 0 0 0 0 0 0 0 27 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 80 0 0 0 % W
% Tyr: 0 7 0 7 0 67 0 74 0 14 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _