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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK1D All Species: 7.95
Human Site: S411 Identified Species: 13.46
UniProt: P48730 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48730 NP_001884.2 415 47330 S411 V A S S G L Q S V V H R _ _ _
Chimpanzee Pan troglodytes XP_001167759 427 49046 A411 M A S L R L H A A R Q G T R C
Rhesus Macaque Macaca mulatta XP_001113761 317 36681
Dog Lupus familis XP_533137 393 45057
Cat Felis silvestris
Mouse Mus musculus Q9DC28 415 47298 S411 V A S S G L Q S V V H R _ _ _
Rat Rattus norvegicus P97633 325 37477
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLL1 416 47453
Frog Xenopus laevis Q5BP74 415 47421 S411 V T S S G L P S T V H R _ _ _
Zebra Danio Brachydanio rerio Q6P3K7 409 46813
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76324 440 47939 G435 P S G G G G G G V G N A K _ _
Honey Bee Apis mellifera XP_395574 413 47530 Q409 D A A A G E M Q P K T K _ _ _
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_779963 435 49455 K418 G A T S T G M K S A D E G A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42158 450 50928 D445 I D N L Q V S D E H H P H _ _
Baker's Yeast Sacchar. cerevisiae P29295 494 57322 M475 Q A S V P P Q M R S N P Q Q P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 76.1 90.3 N.A. 99.7 56.8 N.A. N.A. 83.8 96.6 91 N.A. 62.5 66.7 N.A. 71
Protein Similarity: 100 95.3 76.3 91.5 N.A. 100 65.3 N.A. N.A. 88.9 97.8 94.6 N.A. 72 77.1 N.A. 78.8
P-Site Identity: 100 20 0 0 N.A. 100 0 N.A. N.A. 0 75 0 N.A. 15.3 16.6 N.A. 13.3
P-Site Similarity: 100 33.3 0 0 N.A. 100 0 N.A. N.A. 0 75 0 N.A. 30.7 41.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 56.6 47.7 N.A.
Protein Similarity: N.A. N.A. N.A. 69.5 63.7 N.A.
P-Site Identity: N.A. N.A. N.A. 7.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 30.7 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 43 8 8 0 0 0 8 8 8 0 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 8 8 0 0 0 0 0 8 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 8 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 8 36 15 8 8 0 8 0 8 8 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 8 29 0 8 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 8 0 8 0 8 8 0 0 % K
% Leu: 0 0 0 15 0 29 0 0 0 0 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 15 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 15 0 0 0 0 % N
% Pro: 8 0 0 0 8 8 8 0 8 0 0 15 0 0 8 % P
% Gln: 8 0 0 0 8 0 22 8 0 0 8 0 8 8 0 % Q
% Arg: 0 0 0 0 8 0 0 0 8 8 0 22 0 8 0 % R
% Ser: 0 8 36 29 0 0 8 22 8 8 0 0 0 0 0 % S
% Thr: 0 8 8 0 8 0 0 0 8 0 8 0 8 0 0 % T
% Val: 22 0 0 8 0 8 0 0 22 22 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 29 43 43 % _