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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK1D All Species: 18.48
Human Site: T355 Identified Species: 31.28
UniProt: P48730 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48730 NP_001884.2 415 47330 T355 P T S H T A N T S P R P V S G
Chimpanzee Pan troglodytes XP_001167759 427 49046 T355 P T S H T A N T S P R P V S G
Rhesus Macaque Macaca mulatta XP_001113761 317 36681 L258 Y L N F C R S L R F D D K P D
Dog Lupus familis XP_533137 393 45057 S334 P T P L T P T S H T A N T S P
Cat Felis silvestris
Mouse Mus musculus Q9DC28 415 47298 T355 P T S H T A N T S P R P V S G
Rat Rattus norvegicus P97633 325 37477 L266 Y L N Y C R G L R F E E A P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLL1 416 47453 Q357 S T P T S R I Q Q S G N T S P
Frog Xenopus laevis Q5BP74 415 47421 T355 P T S H T A N T S P R P V S G
Zebra Danio Brachydanio rerio Q6P3K7 409 46813 H350 T P L T P T S H T A N T S S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76324 440 47939 I379 G G N G S Q L I G G N G L N M
Honey Bee Apis mellifera XP_395574 413 47530 G353 G T V G P T V G G T T T N L R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_779963 435 49455 T362 A V G G F H A T S P R P V S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42158 450 50928 S389 S R R V T A V S G S R D N F P
Baker's Yeast Sacchar. cerevisiae P29295 494 57322 N419 Q Q L Q Q Q P N G Q R P N Y Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 76.1 90.3 N.A. 99.7 56.8 N.A. N.A. 83.8 96.6 91 N.A. 62.5 66.7 N.A. 71
Protein Similarity: 100 95.3 76.3 91.5 N.A. 100 65.3 N.A. N.A. 88.9 97.8 94.6 N.A. 72 77.1 N.A. 78.8
P-Site Identity: 100 100 0 26.6 N.A. 100 0 N.A. N.A. 13.3 100 6.6 N.A. 0 6.6 N.A. 46.6
P-Site Similarity: 100 100 13.3 33.3 N.A. 100 13.3 N.A. N.A. 20 100 20 N.A. 26.6 6.6 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 56.6 47.7 N.A.
Protein Similarity: N.A. N.A. N.A. 69.5 63.7 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 36 8 0 0 8 8 0 8 0 0 % A
% Cys: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 15 0 0 15 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % E
% Phe: 0 0 0 8 8 0 0 0 0 15 0 0 0 8 0 % F
% Gly: 15 8 8 22 0 0 8 8 29 8 8 8 0 0 29 % G
% His: 0 0 0 29 0 8 0 8 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 15 15 8 0 0 8 15 0 0 0 0 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 22 0 0 0 29 8 0 0 15 15 22 8 0 % N
% Pro: 36 8 15 0 15 8 8 0 0 36 0 43 0 15 29 % P
% Gln: 8 8 0 8 8 15 0 8 8 8 0 0 0 0 0 % Q
% Arg: 0 8 8 0 0 22 0 0 15 0 50 0 0 0 15 % R
% Ser: 15 0 29 0 15 0 15 15 36 15 0 0 8 58 0 % S
% Thr: 8 50 0 15 43 15 8 36 8 15 8 15 15 0 0 % T
% Val: 0 8 8 8 0 0 15 0 0 0 0 0 36 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 8 0 0 0 0 0 0 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _