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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK1D All Species: 20.3
Human Site: T387 Identified Species: 34.36
UniProt: P48730 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48730 NP_001884.2 415 47330 T387 N I S S S D L T G R Q D T S R
Chimpanzee Pan troglodytes XP_001167759 427 49046 T387 N I S S S D L T G R Q D T S R
Rhesus Macaque Macaca mulatta XP_001113761 317 36681 W290 S Y D Y V F D W N M L K F G A
Dog Lupus familis XP_533137 393 45057 S366 R G A P V N I S S S D L T G R
Cat Felis silvestris
Mouse Mus musculus Q9DC28 415 47298 T387 N V S S S D L T G R Q D T S R
Rat Rattus norvegicus P97633 325 37477 W298 Q Y D Y T F D W T M L K Q K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLL1 416 47453 S389 R G A P A N V S S S D L T G R
Frog Xenopus laevis Q5BP74 415 47421 T387 N V S S S D L T S R Q D T S R
Zebra Danio Brachydanio rerio Q6P3K7 409 46813 S382 R G A P V N V S S S D L T G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76324 440 47939 M411 E R R P S I R M R Q G G G G G
Honey Bee Apis mellifera XP_395574 413 47530 S385 Q E S D L Q A S G T G G Q E R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_779963 435 49455 V394 G P P S S D P V Q R G D Y G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42158 450 50928 G421 V I P R N S P G E A G K S T R
Baker's Yeast Sacchar. cerevisiae P29295 494 57322 R451 Q V P M A T T R A T Q Y P P Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 76.1 90.3 N.A. 99.7 56.8 N.A. N.A. 83.8 96.6 91 N.A. 62.5 66.7 N.A. 71
Protein Similarity: 100 95.3 76.3 91.5 N.A. 100 65.3 N.A. N.A. 88.9 97.8 94.6 N.A. 72 77.1 N.A. 78.8
P-Site Identity: 100 100 0 13.3 N.A. 93.3 0 N.A. N.A. 13.3 86.6 13.3 N.A. 6.6 20 N.A. 40
P-Site Similarity: 100 100 6.6 40 N.A. 100 6.6 N.A. N.A. 46.6 93.3 40 N.A. 13.3 26.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. 56.6 47.7 N.A.
Protein Similarity: N.A. N.A. N.A. 69.5 63.7 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 22 0 15 0 8 0 8 8 0 0 0 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 15 8 0 36 15 0 0 0 22 36 0 0 0 % D
% Glu: 8 8 0 0 0 0 0 0 8 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 15 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 22 0 0 0 0 0 8 29 0 29 15 8 43 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 22 0 0 0 8 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 22 0 8 0 % K
% Leu: 0 0 0 0 8 0 29 0 0 0 15 22 0 0 0 % L
% Met: 0 0 0 8 0 0 0 8 0 15 0 0 0 0 0 % M
% Asn: 29 0 0 0 8 22 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 8 22 29 0 0 15 0 0 0 0 0 8 8 0 % P
% Gln: 22 0 0 0 0 8 0 0 8 8 36 0 15 0 8 % Q
% Arg: 22 8 8 8 0 0 8 8 8 36 0 0 0 0 72 % R
% Ser: 8 0 36 36 43 8 0 29 29 22 0 0 8 29 0 % S
% Thr: 0 0 0 0 8 8 8 29 8 15 0 0 50 8 0 % T
% Val: 8 22 0 0 22 0 15 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % W
% Tyr: 0 15 0 15 0 0 0 0 0 0 0 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _