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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK1D All Species: 39.7
Human Site: Y118 Identified Species: 67.18
UniProt: P48730 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48730 NP_001884.2 415 47330 Y118 Q M I S R I E Y I H S K N F I
Chimpanzee Pan troglodytes XP_001167759 427 49046 Y118 Q M I S R I E Y I H S K N F I
Rhesus Macaque Macaca mulatta XP_001113761 317 36681 A36 I A A G E E V A I K L E C V K
Dog Lupus familis XP_533137 393 45057 D112 S K N F I H R D V K P D N F L
Cat Felis silvestris
Mouse Mus musculus Q9DC28 415 47298 Y118 Q M I S R I E Y I H S K N F I
Rat Rattus norvegicus P97633 325 37477 A44 I T N G E E V A V K L E S Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLL1 416 47453 Y118 Q M I S R I E Y I H S K N F I
Frog Xenopus laevis Q5BP74 415 47421 Y118 Q M I S R I E Y I H S K N F I
Zebra Danio Brachydanio rerio Q6P3K7 409 46813 Y118 Q M I S R I E Y I H S K N F I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76324 440 47939 Y118 Q M I S R I D Y I H S R D F I
Honey Bee Apis mellifera XP_395574 413 47530 Y118 Q L I S R T D Y I H S R N F I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_779963 435 49455 Y118 Q L I S R I E Y V H S K N F I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42158 450 50928 F118 Q M I N R V E F F H S K S F L
Baker's Yeast Sacchar. cerevisiae P29295 494 57322 Y118 Q M F C R I Q Y I H G R S F I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 76.1 90.3 N.A. 99.7 56.8 N.A. N.A. 83.8 96.6 91 N.A. 62.5 66.7 N.A. 71
Protein Similarity: 100 95.3 76.3 91.5 N.A. 100 65.3 N.A. N.A. 88.9 97.8 94.6 N.A. 72 77.1 N.A. 78.8
P-Site Identity: 100 100 6.6 13.3 N.A. 100 0 N.A. N.A. 100 100 100 N.A. 80 73.3 N.A. 86.6
P-Site Similarity: 100 100 13.3 26.6 N.A. 100 20 N.A. N.A. 100 100 100 N.A. 100 93.3 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. 56.6 47.7 N.A.
Protein Similarity: N.A. N.A. N.A. 69.5 63.7 N.A.
P-Site Identity: N.A. N.A. N.A. 60 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 93.3 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 0 15 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 15 8 0 0 0 8 8 0 0 % D
% Glu: 0 0 0 0 15 15 58 0 0 0 0 15 0 0 0 % E
% Phe: 0 0 8 8 0 0 0 8 8 0 0 0 0 86 0 % F
% Gly: 0 0 0 15 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 79 0 0 0 0 0 % H
% Ile: 15 0 72 0 8 65 0 0 72 0 0 0 0 0 72 % I
% Lys: 0 8 0 0 0 0 0 0 0 22 0 58 0 0 15 % K
% Leu: 0 15 0 0 0 0 0 0 0 0 15 0 0 0 15 % L
% Met: 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 15 8 0 0 0 0 0 0 0 0 65 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % P
% Gln: 79 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 79 0 8 0 0 0 0 22 0 0 0 % R
% Ser: 8 0 0 65 0 0 0 0 0 0 72 0 22 0 0 % S
% Thr: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 8 15 0 22 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 72 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _