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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PITPNB All Species: 44.55
Human Site: S25 Identified Species: 98
UniProt: P48739 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48739 NP_036531.1 271 31540 S25 Y Q V G Q L Y S V A E A S K N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001101197 272 31620 S25 Y Q V G Q L Y S V A E A S K N
Dog Lupus familis XP_851991 272 31647 S25 Y Q V G Q L Y S V A E A S K N
Cat Felis silvestris
Mouse Mus musculus P53811 271 31468 S25 Y Q V G Q L Y S V A E A S K N
Rat Rattus norvegicus P53812 271 31431 S25 Y Q V G Q L Y S V A E A S K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508779 330 37294 S84 Y Q V G Q L Y S V A E A S K N
Chicken Gallus gallus NP_001034355 272 31702 S25 Y Q V G Q L Y S V A E A S K N
Frog Xenopus laevis NP_001086964 271 31542 S25 Y Q V G Q L Y S V A E A S K N
Zebra Danio Brachydanio rerio NP_957214 272 31754 S25 Y Q V G Q L F S V A E A S K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524404 272 31268 S24 Y Q V A Q L F S V A E A S K E
Honey Bee Apis mellifera XP_624564 271 31530 S24 Y Q V A Q L Y S V A E A S K N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.7 97.4 N.A. 97.4 97.7 N.A. 76 91.1 87.8 84.1 N.A. 63.9 61.6 N.A. N.A.
Protein Similarity: 100 N.A. 98.5 98.5 N.A. 98.5 98.8 N.A. 80.3 94.4 94.8 91.1 N.A. 76.8 76.7 N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 80 93.3 N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 86.6 93.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 0 0 0 0 100 0 100 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 82 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % K
% Leu: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 100 0 0 100 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 0 0 100 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 100 0 0 0 0 0 100 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 100 0 0 0 0 0 82 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _