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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LHX1 All Species: 18.48
Human Site: S123 Identified Species: 33.89
UniProt: P48742 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48742 NP_005559.2 406 44808 S123 E D Y L S N S S V A K E N S L
Chimpanzee Pan troglodytes Q5IS44 406 44776 S123 E D Y L S N S S V A K E N S L
Rhesus Macaque Macaca mulatta XP_001111705 402 44357 S124 D D Y L S S S S L K E G S L N
Dog Lupus familis XP_852897 464 51133 S181 E D Y L S N S S V A K E N S L
Cat Felis silvestris
Mouse Mus musculus P53776 390 43059 Q100 Q Q G I P P T Q V V R K A Q D
Rat Rattus norvegicus P63007 406 44762 S123 E D Y L S N S S V A K E N S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517055 231 26095
Chicken Gallus gallus P53411 406 44827 N123 E D Y L N N S N T A K E N S L
Frog Xenopus laevis P29674 403 44916 N123 E D Y L N N N N A A K E N S F
Zebra Danio Brachydanio rerio Q90476 405 45135 N123 D D Y L S N T N G K D S N L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRC7 275 31013
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P20154 405 45759 S103 C D C R A P M S M T C F S R D
Sea Urchin Strong. purpuratus NP_999810 480 53702 Q124 E D Y L T K C Q L R R P E L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 73.8 87.2 N.A. 36.2 99.5 N.A. 46.7 94.3 92.1 87.9 N.A. 31.7 N.A. 40.1 52.9
Protein Similarity: 100 99.7 84.4 87.2 N.A. 52.4 99.7 N.A. 52.4 96.8 96 94.3 N.A. 43.3 N.A. 54.9 62.7
P-Site Identity: 100 100 40 100 N.A. 6.6 100 N.A. 0 80 66.6 46.6 N.A. 0 N.A. 13.3 26.6
P-Site Similarity: 100 100 73.3 100 N.A. 40 100 N.A. 0 93.3 86.6 66.6 N.A. 0 N.A. 33.3 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 8 47 0 0 8 0 0 % A
% Cys: 8 0 8 0 0 0 8 0 0 0 8 0 0 0 0 % C
% Asp: 16 77 0 0 0 0 0 0 0 0 8 0 0 0 16 % D
% Glu: 54 0 0 0 0 0 0 0 0 0 8 47 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % F
% Gly: 0 0 8 0 0 0 0 0 8 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 16 47 8 0 0 0 % K
% Leu: 0 0 0 70 0 0 0 0 16 0 0 0 0 24 47 % L
% Met: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 16 54 8 24 0 0 0 0 54 0 8 % N
% Pro: 0 0 0 0 8 16 0 0 0 0 0 8 0 0 8 % P
% Gln: 8 8 0 0 0 0 0 16 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 8 16 0 0 8 0 % R
% Ser: 0 0 0 0 47 8 47 47 0 0 0 8 16 47 0 % S
% Thr: 0 0 0 0 8 0 16 0 8 8 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 39 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 70 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _