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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX1
All Species:
22.42
Human Site:
S337
Identified Species:
41.11
UniProt:
P48742
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48742
NP_005559.2
406
44808
S337
P
L
P
G
H
H
P
S
S
E
A
Q
R
F
T
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
S337
P
L
P
G
H
H
P
S
S
E
A
Q
R
F
T
Rhesus Macaque
Macaca mulatta
XP_001111705
402
44357
D337
L
A
G
P
H
A
A
D
N
P
R
F
T
D
M
Dog
Lupus familis
XP_852897
464
51133
S395
P
L
P
G
H
H
P
S
S
E
A
Q
R
F
T
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
P321
P
S
S
I
S
S
L
P
S
H
A
P
L
L
N
Rat
Rattus norvegicus
P63007
406
44762
S337
P
L
P
G
H
H
P
S
S
E
A
Q
R
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517055
231
26095
Q166
H
I
R
E
Q
L
A
Q
E
T
G
L
N
M
R
Chicken
Gallus gallus
P53411
406
44827
P337
P
L
P
G
H
H
P
P
G
E
A
Q
R
F
P
Frog
Xenopus laevis
P29674
403
44916
S336
P
I
P
G
H
H
P
S
S
D
A
Q
R
F
T
Zebra Danio
Brachydanio rerio
Q90476
405
45135
S336
P
I
P
G
H
H
P
S
S
E
V
Q
R
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
G210
Q
K
K
H
I
H
A
G
K
N
K
I
R
E
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20154
405
45759
P334
Q
F
Y
P
P
P
P
P
S
N
V
Q
F
F
C
Sea Urchin
Strong. purpuratus
NP_999810
480
53702
P405
V
L
G
G
G
I
P
P
D
G
S
E
Y
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
73.8
87.2
N.A.
36.2
99.5
N.A.
46.7
94.3
92.1
87.9
N.A.
31.7
N.A.
40.1
52.9
Protein Similarity:
100
99.7
84.4
87.2
N.A.
52.4
99.7
N.A.
52.4
96.8
96
94.3
N.A.
43.3
N.A.
54.9
62.7
P-Site Identity:
100
100
6.6
100
N.A.
20
100
N.A.
0
80
86.6
80
N.A.
13.3
N.A.
26.6
20
P-Site Similarity:
100
100
13.3
100
N.A.
20
100
N.A.
6.6
80
100
93.3
N.A.
13.3
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
24
0
0
0
54
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
8
8
8
0
0
0
8
0
% D
% Glu:
0
0
0
8
0
0
0
0
8
47
0
8
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
8
8
62
0
% F
% Gly:
0
0
16
62
8
0
0
8
8
8
8
0
0
0
0
% G
% His:
8
0
0
8
62
62
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
24
0
8
8
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
8
0
8
0
0
0
0
% K
% Leu:
8
47
0
0
0
8
8
0
0
0
0
8
8
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
0
0
0
0
0
0
8
16
0
0
8
0
8
% N
% Pro:
62
0
54
16
8
8
70
31
0
8
0
8
0
0
16
% P
% Gln:
16
0
0
0
8
0
0
8
0
0
0
62
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
8
0
62
0
8
% R
% Ser:
0
8
8
0
8
8
0
47
62
0
8
0
0
0
16
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
39
% T
% Val:
8
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _