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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX1
All Species:
15.45
Human Site:
S389
Identified Species:
28.33
UniProt:
P48742
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48742
NP_005559.2
406
44808
S389
L
S
V
N
G
G
A
S
Y
G
N
H
L
S
H
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
S389
L
S
V
N
G
G
A
S
Y
G
N
H
L
S
H
Rhesus Macaque
Macaca mulatta
XP_001111705
402
44357
L389
T
S
G
Y
S
G
P
L
S
H
P
N
P
E
L
Dog
Lupus familis
XP_852897
464
51133
S447
L
S
V
N
G
G
A
S
Y
G
N
H
L
S
H
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
D373
G
S
S
V
G
Y
P
D
F
P
T
S
P
A
S
Rat
Rattus norvegicus
P63007
406
44762
S389
L
S
V
N
G
G
A
S
Y
G
N
H
L
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517055
231
26095
E218
P
L
G
G
R
L
D
E
S
E
M
L
G
S
T
Chicken
Gallus gallus
P53411
406
44827
N389
I
S
V
N
G
G
A
N
Y
G
N
H
L
S
H
Frog
Xenopus laevis
P29674
403
44916
G388
L
S
V
N
G
G
Y
G
N
H
L
S
H
P
P
Zebra Danio
Brachydanio rerio
Q90476
405
45135
Y388
L
S
L
N
G
S
G
Y
S
N
H
L
S
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
L262
H
E
S
S
M
D
E
L
S
Q
D
S
S
V
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20154
405
45759
E386
A
T
P
P
E
F
N
E
D
T
F
A
C
I
Y
Sea Urchin
Strong. purpuratus
NP_999810
480
53702
A457
F
G
P
P
R
G
G
A
H
P
P
H
V
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
73.8
87.2
N.A.
36.2
99.5
N.A.
46.7
94.3
92.1
87.9
N.A.
31.7
N.A.
40.1
52.9
Protein Similarity:
100
99.7
84.4
87.2
N.A.
52.4
99.7
N.A.
52.4
96.8
96
94.3
N.A.
43.3
N.A.
54.9
62.7
P-Site Identity:
100
100
13.3
100
N.A.
13.3
100
N.A.
6.6
86.6
40
26.6
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
100
20
100
N.A.
26.6
100
N.A.
6.6
100
40
40
N.A.
20
N.A.
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
39
8
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
8
8
8
8
0
8
0
0
0
0
% D
% Glu:
0
8
0
0
8
0
8
16
0
8
0
0
0
8
0
% E
% Phe:
8
0
0
0
0
8
0
0
8
0
8
0
0
0
0
% F
% Gly:
8
8
16
8
62
62
16
8
0
39
0
0
8
0
8
% G
% His:
8
0
0
0
0
0
0
0
8
16
8
47
8
8
47
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
47
8
8
0
0
8
0
16
0
0
8
16
39
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
54
0
0
8
8
8
8
39
8
0
8
0
% N
% Pro:
8
0
16
16
0
0
16
0
0
16
16
0
16
8
16
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
70
16
8
8
8
0
31
31
0
0
24
16
47
8
% S
% Thr:
8
8
0
0
0
0
0
0
0
8
8
0
0
0
8
% T
% Val:
0
0
47
8
0
0
0
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
8
8
39
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _