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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX1
All Species:
39.7
Human Site:
T186
Identified Species:
72.78
UniProt:
P48742
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48742
NP_005559.2
406
44808
T186
K
R
R
G
P
R
T
T
I
K
A
K
Q
L
E
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
T186
K
R
R
G
P
R
T
T
I
K
A
K
Q
L
E
Rhesus Macaque
Macaca mulatta
XP_001111705
402
44357
T186
K
R
R
G
P
R
T
T
I
K
A
K
Q
L
E
Dog
Lupus familis
XP_852897
464
51133
T244
K
R
R
G
P
R
T
T
I
K
A
K
Q
L
E
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
T163
G
A
K
R
P
R
T
T
I
T
A
K
Q
L
E
Rat
Rattus norvegicus
P63007
406
44762
T186
K
R
R
G
P
R
T
T
I
K
A
K
Q
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517055
231
26095
P24
G
C
A
Q
G
I
S
P
S
D
L
V
R
K
A
Chicken
Gallus gallus
P53411
406
44827
T186
K
R
R
G
P
R
T
T
I
K
A
K
Q
L
E
Frog
Xenopus laevis
P29674
403
44916
T185
K
R
R
G
P
R
T
T
I
K
A
K
Q
L
E
Zebra Danio
Brachydanio rerio
Q90476
405
45135
T185
K
R
R
G
P
R
T
T
I
K
A
K
Q
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
K68
Y
S
K
N
F
G
A
K
C
S
K
C
C
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20154
405
45759
G165
C
Q
R
L
L
D
T
G
D
Q
L
Y
I
M
E
Sea Urchin
Strong. purpuratus
NP_999810
480
53702
T238
K
R
R
G
P
R
T
T
I
K
A
K
Q
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
73.8
87.2
N.A.
36.2
99.5
N.A.
46.7
94.3
92.1
87.9
N.A.
31.7
N.A.
40.1
52.9
Protein Similarity:
100
99.7
84.4
87.2
N.A.
52.4
99.7
N.A.
52.4
96.8
96
94.3
N.A.
43.3
N.A.
54.9
62.7
P-Site Identity:
100
100
100
100
N.A.
66.6
100
N.A.
0
100
100
100
N.A.
0
N.A.
20
100
P-Site Similarity:
100
100
100
100
N.A.
73.3
100
N.A.
13.3
100
100
100
N.A.
6.6
N.A.
40
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
8
0
0
0
77
0
0
0
8
% A
% Cys:
8
8
0
0
0
0
0
0
8
0
0
8
8
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
8
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
85
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
70
8
8
0
8
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
77
0
0
0
8
0
0
% I
% Lys:
70
0
16
0
0
0
0
8
0
70
8
77
0
8
0
% K
% Leu:
0
0
0
8
8
0
0
0
0
0
16
0
0
77
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
77
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
8
0
0
77
0
0
% Q
% Arg:
0
70
77
8
0
77
0
0
0
0
0
0
8
8
0
% R
% Ser:
0
8
0
0
0
0
8
0
8
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
85
77
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _