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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A3 All Species: 1.21
Human Site: S746 Identified Species: 2.67
UniProt: P48764 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48764 NP_004165.2 834 92855 S746 S V T K D T A S D S P A G I D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851881 897 99179 S741 V L Q E G K V S G S L E V C P
Cat Felis silvestris
Mouse Mus musculus Q61165 820 91449 L700 H K L D S P T L S R A R I G S
Rat Rattus norvegicus P26433 831 93087 D744 V T K D V A S D S G A G I D N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520936 855 95995 A764 A N V T Q D P A T D S T T G I
Chicken Gallus gallus Q5ZJ75 574 64115 M490 N L S K T E K M G N T I E S E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001106944 832 93065 P748 M G A G I E N P V F M P D M D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391857 1107 124590 N909 S C R S V S L N V K R D E R E
Nematode Worm Caenorhab. elegans P35449 667 75263 I582 F M E S G E N I D S L Y T L F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 G451 D S H D T S L G D G F E V V N
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 N549 S S N K N L P N N I S T T G G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 50.3 N.A. 38.6 88.8 N.A. 78.8 21.8 N.A. 50.9 N.A. N.A. 32.5 34.2 N.A.
Protein Similarity: 100 N.A. N.A. 65.3 N.A. 58.6 92.9 N.A. 85.9 38.2 N.A. 67.2 N.A. N.A. 49.4 53.7 N.A.
P-Site Identity: 100 N.A. N.A. 13.3 N.A. 0 0 N.A. 0 6.6 N.A. 6.6 N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 0 13.3 N.A. 13.3 40 N.A. 13.3 N.A. N.A. 26.6 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.8 23.8 N.A.
Protein Similarity: N.A. N.A. N.A. 36.4 41 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 10 10 10 0 0 19 10 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 10 0 0 28 10 10 0 10 28 10 0 10 10 10 19 % D
% Glu: 0 0 10 10 0 28 0 0 0 0 0 19 19 0 19 % E
% Phe: 10 0 0 0 0 0 0 0 0 10 10 0 0 0 10 % F
% Gly: 0 10 0 10 19 0 0 10 19 19 0 10 10 28 10 % G
% His: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 10 0 10 0 10 19 10 10 % I
% Lys: 0 10 10 28 0 10 10 0 0 10 0 0 0 0 0 % K
% Leu: 0 19 10 0 0 10 19 10 0 0 19 0 0 10 0 % L
% Met: 10 10 0 0 0 0 0 10 0 0 10 0 0 10 0 % M
% Asn: 10 10 10 0 10 0 19 19 10 10 0 0 0 0 19 % N
% Pro: 0 0 0 0 0 10 19 10 0 0 10 10 0 0 10 % P
% Gln: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 10 10 10 0 10 0 % R
% Ser: 28 19 10 19 10 19 10 19 19 28 19 0 0 10 10 % S
% Thr: 0 10 10 10 19 10 10 0 10 0 10 19 28 0 0 % T
% Val: 19 10 10 0 19 0 10 0 19 0 0 0 19 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _