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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A3 All Species: 8.18
Human Site: T578 Identified Species: 18
UniProt: P48764 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48764 NP_004165.2 834 92855 T578 D F T P R S S T V E A S V S Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851881 897 99179 L573 A E T S V T N L L R E S G S G
Cat Felis silvestris
Mouse Mus musculus Q61165 820 91449 D532 E I H T Q F L D H L L T G I E
Rat Rattus norvegicus P26433 831 93087 T576 F S T P R P S T V E A S V S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520936 855 95995 S596 F S S R R P S S V E A S V S Y
Chicken Gallus gallus Q5ZJ75 574 64115 I322 M A I L F S G I V M S H Y T H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001106944 832 93065 F580 K K Q F D S E F A D V M P D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391857 1107 124590 G741 S N T G Q F N G S P S C S Q L
Nematode Worm Caenorhab. elegans P35449 667 75263 T414 V S I P A S I T A K P M F I T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 V283 G L S L S G I V S I L F T G I
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 V381 Y K P L L I I V A A I S I C V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 50.3 N.A. 38.6 88.8 N.A. 78.8 21.8 N.A. 50.9 N.A. N.A. 32.5 34.2 N.A.
Protein Similarity: 100 N.A. N.A. 65.3 N.A. 58.6 92.9 N.A. 85.9 38.2 N.A. 67.2 N.A. N.A. 49.4 53.7 N.A.
P-Site Identity: 100 N.A. N.A. 20 N.A. 0 80 N.A. 60 13.3 N.A. 6.6 N.A. N.A. 6.6 20 N.A.
P-Site Similarity: 100 N.A. N.A. 40 N.A. 20 80 N.A. 73.3 33.3 N.A. 13.3 N.A. N.A. 26.6 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.8 23.8 N.A.
Protein Similarity: N.A. N.A. N.A. 36.4 41 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 10 0 0 0 28 10 28 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % C
% Asp: 10 0 0 0 10 0 0 10 0 10 0 0 0 10 0 % D
% Glu: 10 10 0 0 0 0 10 0 0 28 10 0 0 0 10 % E
% Phe: 19 10 0 10 10 19 0 10 0 0 0 10 10 0 0 % F
% Gly: 10 0 0 10 0 10 10 10 0 0 0 0 19 10 10 % G
% His: 0 0 10 0 0 0 0 0 10 0 0 10 0 0 10 % H
% Ile: 0 10 19 0 0 10 28 10 0 10 10 0 10 19 19 % I
% Lys: 10 19 0 0 0 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 0 10 0 28 10 0 10 10 10 10 19 0 0 0 10 % L
% Met: 10 0 0 0 0 0 0 0 0 10 0 19 0 0 0 % M
% Asn: 0 10 0 0 0 0 19 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 28 0 19 0 0 0 10 10 0 10 0 0 % P
% Gln: 0 0 10 0 19 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 10 28 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 10 28 19 10 10 37 28 10 19 0 19 46 10 37 0 % S
% Thr: 0 0 37 10 0 10 0 28 0 0 0 10 10 10 10 % T
% Val: 10 0 0 0 10 0 0 19 37 0 10 0 28 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 28 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _