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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC9A3
All Species:
10
Human Site:
T616
Identified Species:
22
UniProt:
P48764
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48764
NP_004165.2
834
92855
T616
R
D
A
E
D
M
V
T
H
H
T
L
Q
Q
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851881
897
99179
Y611
H
L
L
C
G
G
L
Y
K
P
R
R
R
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61165
820
91449
E570
K
K
C
L
I
A
G
E
R
S
K
E
P
Q
L
Rat
Rattus norvegicus
P26433
831
93087
T614
R
D
T
E
D
M
V
T
H
H
T
L
Q
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520936
855
95995
T634
R
D
T
E
D
M
V
T
H
H
T
L
Q
Q
Y
Chicken
Gallus gallus
Q5ZJ75
574
64115
G360
T
C
V
F
A
F
L
G
L
S
I
F
S
F
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001106944
832
93065
I618
I
P
S
V
S
L
D
I
H
G
Q
D
G
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391857
1107
124590
E779
R
I
H
H
L
L
A
E
E
L
C
K
P
Y
K
Nematode Worm
Caenorhab. elegans
P35449
667
75263
E452
L
K
I
K
K
K
E
E
R
D
P
T
M
V
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWU6
535
59320
T321
L
I
S
S
L
A
E
T
F
V
F
I
Y
M
G
Baker's Yeast
Sacchar. cerevisiae
Q04121
633
70130
E419
S
M
S
G
I
T
G
E
N
I
S
V
P
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
50.3
N.A.
38.6
88.8
N.A.
78.8
21.8
N.A.
50.9
N.A.
N.A.
32.5
34.2
N.A.
Protein Similarity:
100
N.A.
N.A.
65.3
N.A.
58.6
92.9
N.A.
85.9
38.2
N.A.
67.2
N.A.
N.A.
49.4
53.7
N.A.
P-Site Identity:
100
N.A.
N.A.
0
N.A.
6.6
93.3
N.A.
93.3
0
N.A.
6.6
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
13.3
93.3
N.A.
93.3
6.6
N.A.
26.6
N.A.
N.A.
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
23.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.4
41
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
19
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
10
10
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
28
0
0
28
0
10
0
0
10
0
10
0
10
0
% D
% Glu:
0
0
0
28
0
0
19
37
10
0
0
10
0
0
19
% E
% Phe:
0
0
0
10
0
10
0
0
10
0
10
10
0
10
0
% F
% Gly:
0
0
0
10
10
10
19
10
0
10
0
0
10
0
10
% G
% His:
10
0
10
10
0
0
0
0
37
28
0
0
0
0
0
% H
% Ile:
10
19
10
0
19
0
0
10
0
10
10
10
0
0
0
% I
% Lys:
10
19
0
10
10
10
0
0
10
0
10
10
0
10
19
% K
% Leu:
19
10
10
10
19
19
19
0
10
10
0
28
0
0
10
% L
% Met:
0
10
0
0
0
28
0
0
0
0
0
0
10
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% N
% Pro:
0
10
0
0
0
0
0
0
0
10
10
0
28
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
28
37
0
% Q
% Arg:
37
0
0
0
0
0
0
0
19
0
10
10
10
0
0
% R
% Ser:
10
0
28
10
10
0
0
0
0
19
10
0
10
0
0
% S
% Thr:
10
0
19
0
0
10
0
37
0
0
28
10
0
0
0
% T
% Val:
0
0
10
10
0
0
28
0
0
10
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
10
19
28
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _