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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A3 All Species: 2.12
Human Site: Y546 Identified Species: 4.67
UniProt: P48764 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48764 NP_004165.2 834 92855 Y546 N L K D A I S Y V A E G E R R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851881 897 99179 F541 N I R D A I S F V D Q G G H I
Cat Felis silvestris
Mouse Mus musculus Q61165 820 91449 G500 F F T V F V Q G M T I R P L V
Rat Rattus norvegicus P26433 831 93087 V544 L K D A I S Y V A E G E R R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520936 855 95995 V564 L K D A I S Y V A E G E R R G
Chicken Gallus gallus Q5ZJ75 574 64115 L290 D L R K T P S L E F G M M I I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001106944 832 93065 N548 L N L E D A M N Y V S E G E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391857 1107 124590 Y709 A M K D A L D Y I R R N A S T
Nematode Worm Caenorhab. elegans P35449 667 75263 K382 I L N R F R A K K F E M V D Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 D251 L F K Y A G L D V D N L Q N L
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 L349 T I K Y I F Q L L A R L S E N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 50.3 N.A. 38.6 88.8 N.A. 78.8 21.8 N.A. 50.9 N.A. N.A. 32.5 34.2 N.A.
Protein Similarity: 100 N.A. N.A. 65.3 N.A. 58.6 92.9 N.A. 85.9 38.2 N.A. 67.2 N.A. N.A. 49.4 53.7 N.A.
P-Site Identity: 100 N.A. N.A. 46.6 N.A. 0 6.6 N.A. 6.6 13.3 N.A. 6.6 N.A. N.A. 26.6 13.3 N.A.
P-Site Similarity: 100 N.A. N.A. 73.3 N.A. 13.3 6.6 N.A. 6.6 26.6 N.A. 13.3 N.A. N.A. 46.6 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.8 23.8 N.A.
Protein Similarity: N.A. N.A. N.A. 36.4 41 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 19 37 10 10 0 19 19 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 19 28 10 0 10 10 0 19 0 0 0 10 0 % D
% Glu: 0 0 0 10 0 0 0 0 10 19 19 28 10 19 0 % E
% Phe: 10 19 0 0 19 10 0 10 0 19 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 10 0 0 28 19 19 0 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 10 19 0 0 28 19 0 0 10 0 10 0 0 10 19 % I
% Lys: 0 19 37 10 0 0 0 10 10 0 0 0 0 0 0 % K
% Leu: 37 28 10 0 0 10 10 19 10 0 0 19 0 10 10 % L
% Met: 0 10 0 0 0 0 10 0 10 0 0 19 10 0 0 % M
% Asn: 19 10 10 0 0 0 0 10 0 0 10 10 0 10 10 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 19 0 0 0 10 0 10 0 10 % Q
% Arg: 0 0 19 10 0 10 0 0 0 10 19 10 19 28 19 % R
% Ser: 0 0 0 0 0 19 28 0 0 0 10 0 10 10 0 % S
% Thr: 10 0 10 0 10 0 0 0 0 10 0 0 0 0 10 % T
% Val: 0 0 0 10 0 10 0 19 28 10 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 19 0 0 19 19 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _