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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC9A3
All Species:
9.39
Human Site:
Y681
Identified Species:
20.67
UniProt:
P48764
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48764
NP_004165.2
834
92855
Y681
N
K
K
A
A
K
L
Y
K
R
E
R
A
Q
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851881
897
99179
G676
T
G
R
K
K
K
D
G
L
A
N
T
E
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61165
820
91449
I635
S
K
D
K
E
E
E
I
R
K
I
L
R
S
N
Rat
Rattus norvegicus
P26433
831
93087
Y679
N
K
K
A
A
K
L
Y
K
R
E
R
A
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520936
855
95995
Y699
T
K
K
T
A
K
L
Y
K
R
D
R
G
Q
K
Chicken
Gallus gallus
Q5ZJ75
574
64115
A425
L
R
G
A
I
P
Y
A
L
S
L
H
L
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001106944
832
93065
A683
R
L
E
S
F
K
S
A
K
M
G
V
N
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391857
1107
124590
P844
K
Q
N
H
V
S
F
P
E
F
Q
Q
N
G
S
Nematode Worm
Caenorhab. elegans
P35449
667
75263
R517
F
D
A
S
S
I
V
R
A
Y
E
K
I
T
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWU6
535
59320
Y386
T
H
Q
K
A
L
W
Y
S
G
L
R
G
A
M
Baker's Yeast
Sacchar. cerevisiae
Q04121
633
70130
E484
G
T
T
A
G
M
L
E
V
L
N
I
K
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
50.3
N.A.
38.6
88.8
N.A.
78.8
21.8
N.A.
50.9
N.A.
N.A.
32.5
34.2
N.A.
Protein Similarity:
100
N.A.
N.A.
65.3
N.A.
58.6
92.9
N.A.
85.9
38.2
N.A.
67.2
N.A.
N.A.
49.4
53.7
N.A.
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
6.6
100
N.A.
73.3
6.6
N.A.
13.3
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
33.3
100
N.A.
80
13.3
N.A.
26.6
N.A.
N.A.
26.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
23.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.4
41
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
37
37
0
0
19
10
10
0
0
19
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
10
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
10
0
10
10
10
10
10
0
28
0
10
0
0
% E
% Phe:
10
0
0
0
10
0
10
0
0
10
0
0
0
0
0
% F
% Gly:
10
10
10
0
10
0
0
10
0
10
10
0
19
19
10
% G
% His:
0
10
0
10
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
10
10
0
10
0
0
10
10
10
0
0
% I
% Lys:
10
37
28
28
10
46
0
0
37
10
0
10
10
0
28
% K
% Leu:
10
10
0
0
0
10
37
0
19
10
19
10
10
0
19
% L
% Met:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% M
% Asn:
19
0
10
0
0
0
0
0
0
0
19
0
19
0
10
% N
% Pro:
0
0
0
0
0
10
0
10
0
0
0
0
0
10
0
% P
% Gln:
0
10
10
0
0
0
0
0
0
0
10
10
0
28
0
% Q
% Arg:
10
10
10
0
0
0
0
10
10
28
0
37
10
0
0
% R
% Ser:
10
0
0
19
10
10
10
0
10
10
0
0
0
10
10
% S
% Thr:
28
10
10
10
0
0
0
0
0
0
0
10
0
19
19
% T
% Val:
0
0
0
0
10
0
10
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
37
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _