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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A3 All Species: 2.73
Human Site: Y726 Identified Species: 6
UniProt: P48764 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48764 NP_004165.2 834 92855 Y726 D T E E P P N Y D E E M S G G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851881 897 99179 D721 S E T E K E D D E G I I F V A
Cat Felis silvestris
Mouse Mus musculus Q61165 820 91449 L680 R R Q K A R Q L E Q K I T N Y
Rat Rattus norvegicus P26433 831 93087 Y724 E P E E A T N Y E E I S G G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520936 855 95995 F744 D P E E A G E F D P M Q M S G
Chicken Gallus gallus Q5ZJ75 574 64115 E470 L I R L I G I E D S K A R K R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001106944 832 93065 G728 D S G V G A D G A I S S T F M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391857 1107 124590 A889 D S A I T F T A R T S A A G K
Nematode Worm Caenorhab. elegans P35449 667 75263 Q562 L P D K I S N Q K T M T P K D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 S431 T V L L I G G S T G T M L E A
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 N529 D L G P Y S D N N S P D I S I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 50.3 N.A. 38.6 88.8 N.A. 78.8 21.8 N.A. 50.9 N.A. N.A. 32.5 34.2 N.A.
Protein Similarity: 100 N.A. N.A. 65.3 N.A. 58.6 92.9 N.A. 85.9 38.2 N.A. 67.2 N.A. N.A. 49.4 53.7 N.A.
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 0 40 N.A. 33.3 6.6 N.A. 6.6 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 46.6 53.3 N.A. 40 13.3 N.A. 26.6 N.A. N.A. 26.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.8 23.8 N.A.
Protein Similarity: N.A. N.A. N.A. 36.4 41 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 28 10 0 10 10 0 0 19 10 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 46 0 10 0 0 0 28 10 28 0 0 10 0 0 10 % D
% Glu: 10 10 28 37 0 10 10 10 28 19 10 0 0 10 0 % E
% Phe: 0 0 0 0 0 10 0 10 0 0 0 0 10 10 0 % F
% Gly: 0 0 19 0 10 28 10 10 0 19 0 0 10 28 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 10 28 0 10 0 0 10 19 19 10 0 19 % I
% Lys: 0 0 0 19 10 0 0 0 10 0 19 0 0 19 10 % K
% Leu: 19 10 10 19 0 0 0 10 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 19 19 10 0 10 % M
% Asn: 0 0 0 0 0 0 28 10 10 0 0 0 0 10 0 % N
% Pro: 0 28 0 10 10 10 0 0 0 10 10 0 10 0 0 % P
% Gln: 0 0 10 0 0 0 10 10 0 10 0 10 0 0 0 % Q
% Arg: 10 10 10 0 0 10 0 0 10 0 0 0 10 0 10 % R
% Ser: 10 19 0 0 0 19 0 10 0 19 19 19 10 19 0 % S
% Thr: 10 10 10 0 10 10 10 0 10 19 10 10 19 0 0 % T
% Val: 0 10 0 10 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 19 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _