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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TDO2
All Species:
43.33
Human Site:
S356
Identified Species:
79.44
UniProt:
P48775
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48775
NP_005642.1
406
47872
S356
H
Y
L
R
S
T
V
S
D
R
Y
K
V
F
V
Chimpanzee
Pan troglodytes
XP_001140187
406
47819
S356
H
Y
L
R
S
T
V
S
D
R
Y
K
V
F
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532700
406
47838
S356
H
Y
L
R
S
T
V
S
D
R
Y
K
V
F
V
Cat
Felis silvestris
Mouse
Mus musculus
P48776
406
47738
S356
H
Y
L
R
S
T
V
S
D
R
Y
K
V
F
V
Rat
Rattus norvegicus
P21643
406
47838
S356
Y
Y
L
R
S
T
V
S
D
R
Y
K
V
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510047
406
48019
S356
H
Y
L
R
S
T
V
S
D
R
Y
K
V
F
V
Chicken
Gallus gallus
XP_420377
406
47669
S356
Q
Y
L
R
S
T
V
S
D
R
Y
K
V
F
V
Frog
Xenopus laevis
Q5U4U6
406
47659
S356
Q
Y
L
R
S
T
V
S
D
R
Y
K
V
F
V
Zebra Danio
Brachydanio rerio
Q7SY53
407
47403
S355
H
Y
L
R
S
T
V
S
D
R
Y
K
V
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20351
379
44402
S330
Q
Q
L
G
T
G
G
S
S
G
Y
Q
Y
L
R
Honey Bee
Apis mellifera
XP_394304
392
45793
L342
G
S
S
G
Y
Q
Y
L
K
S
T
L
S
D
R
Nematode Worm
Caenorhab. elegans
Q09474
403
46698
T353
G
Y
M
Y
L
R
S
T
V
S
D
R
Y
K
V
Sea Urchin
Strong. purpuratus
XP_798322
455
51404
S343
H
Y
L
R
S
T
V
S
D
R
Y
K
V
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
94.3
N.A.
88.6
88.6
N.A.
88.4
83.7
81
74.9
N.A.
54.1
50.9
52.2
46.1
Protein Similarity:
100
99.7
N.A.
97.7
N.A.
95.5
95.8
N.A.
94.5
92.3
90.6
85.2
N.A.
70.1
70.1
70.6
61.7
P-Site Identity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
100
93.3
93.3
100
N.A.
20
0
13.3
93.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
93.3
93.3
100
N.A.
33.3
0
33.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
77
0
8
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
77
0
% F
% Gly:
16
0
0
16
0
8
8
0
0
8
0
0
0
0
0
% G
% His:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
77
0
8
0
% K
% Leu:
0
0
85
0
8
0
0
8
0
0
0
8
0
8
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
24
8
0
0
0
8
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
77
0
8
0
0
0
77
0
8
0
0
16
% R
% Ser:
0
8
8
0
77
0
8
85
8
16
0
0
8
0
0
% S
% Thr:
0
0
0
0
8
77
0
8
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
77
0
8
0
0
0
77
0
77
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
85
0
8
8
0
8
0
0
0
85
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _