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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNNI2
All Species:
35.45
Human Site:
Y80
Identified Species:
70.91
UniProt:
P48788
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48788
NP_001139301.1
182
21339
Y80
D
A
A
E
E
E
K
Y
D
M
E
V
R
V
Q
Chimpanzee
Pan troglodytes
XP_001153267
182
21292
Y80
D
A
A
E
E
E
K
Y
D
M
E
V
R
V
Q
Rhesus Macaque
Macaca mulatta
XP_001117040
182
21294
Y80
D
A
A
E
E
E
K
Y
D
M
E
V
K
V
Q
Dog
Lupus familis
XP_851068
182
21393
Y80
D
A
A
E
E
E
K
Y
D
M
E
V
R
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
P13412
182
21339
Y80
D
V
A
E
E
E
K
Y
D
M
E
V
K
V
Q
Rat
Rattus norvegicus
P27768
182
21310
Y80
D
A
A
E
E
E
K
Y
D
M
E
V
K
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518819
162
18714
E72
R
V
Q
K
T
T
K
E
L
E
D
L
N
Q
K
Chicken
Gallus gallus
P68246
183
21216
Y80
D
S
V
D
E
E
R
Y
D
T
E
V
K
L
Q
Frog
Xenopus laevis
P50754
244
28179
Y137
D
V
V
D
E
E
R
Y
D
M
E
A
K
V
N
Zebra Danio
Brachydanio rerio
NP_991305
176
20078
Y76
D
K
V
D
E
E
R
Y
D
M
E
A
K
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36188
269
30063
W172
Y
I
C
E
G
Q
K
W
D
L
E
Y
E
V
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9GYF1
242
27542
Y114
T
Q
L
E
E
E
K
Y
D
I
N
Y
V
V
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
98.3
96.1
N.A.
96.6
97.8
N.A.
68.1
81.9
48.3
59.3
N.A.
21.9
N.A.
26
N.A.
Protein Similarity:
100
98.9
100
99.4
N.A.
99.4
100
N.A.
76.9
91.8
61
79.1
N.A.
33.4
N.A.
45
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
86.6
93.3
N.A.
6.6
53.3
53.3
53.3
N.A.
33.3
N.A.
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
33.3
86.6
73.3
73.3
N.A.
60
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
42
50
0
0
0
0
0
0
0
0
17
0
0
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
0
0
25
0
0
0
0
92
0
9
0
0
0
0
% D
% Glu:
0
0
0
67
84
84
0
9
0
9
84
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
9
0
9
0
0
75
0
0
0
0
0
50
0
9
% K
% Leu:
0
0
9
0
0
0
0
0
9
9
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
9
0
0
9
0
0
0
0
0
0
0
9
59
% Q
% Arg:
9
0
0
0
0
0
25
0
0
0
0
0
25
0
9
% R
% Ser:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% S
% Thr:
9
0
0
0
9
9
0
0
0
9
0
0
0
0
0
% T
% Val:
0
25
25
0
0
0
0
0
0
0
0
59
9
84
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
84
0
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _