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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRPC1 All Species: 15.15
Human Site: S21 Identified Species: 33.33
UniProt: P48995 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48995 NP_003295.1 793 91212 S21 A S S S S L P S S P S S S S P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112011 792 91106 S21 A S S S L P S S P S S S S P N
Dog Lupus familis XP_542818 793 91218 S21 A S S S S L P S S P S S S S S
Cat Felis silvestris
Mouse Mus musculus Q61056 809 92709 S37 V S S S S L P S S P S S S S P
Rat Rattus norvegicus Q9QX01 759 87599 S21 V S S S S L P S S P S S S S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505454 837 95954 G65 H H S T E P S G S S S S S S P
Chicken Gallus gallus NP_001004409 781 90059 A21 A S P N K L L A L K D V R Q V
Frog Xenopus laevis NP_001083819 778 90015 D21 N T F L A L K D V R E V K E E
Zebra Danio Brachydanio rerio XP_699455 749 86999 L17 S S S P D K Y L A L K D V R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJJ7 1128 127091 E21 I R Q L T L E E K K F L L A V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34586 1027 118084 R25 A P S P R P R R N Y A L A N I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.8 99.6 N.A. 97.7 94.8 N.A. 88.5 92.4 87.7 79.8 N.A. 28.5 N.A. 28.7 N.A.
Protein Similarity: 100 N.A. 99.8 99.7 N.A. 97.9 95.4 N.A. 92.8 96.8 94.3 88.4 N.A. 45.4 N.A. 46.7 N.A.
P-Site Identity: 100 N.A. 53.3 93.3 N.A. 93.3 93.3 N.A. 46.6 20 6.6 13.3 N.A. 6.6 N.A. 13.3 N.A.
P-Site Similarity: 100 N.A. 53.3 93.3 N.A. 93.3 93.3 N.A. 53.3 33.3 20 26.6 N.A. 20 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 46 0 0 0 10 0 0 10 10 0 10 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 10 0 0 10 10 0 0 0 % D
% Glu: 0 0 0 0 10 0 10 10 0 0 10 0 0 10 19 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 10 10 10 0 10 19 10 0 10 0 0 % K
% Leu: 0 0 0 19 10 64 10 10 10 10 0 19 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 0 0 0 0 10 0 0 0 0 10 10 % N
% Pro: 0 10 10 19 0 28 37 0 10 37 0 0 0 10 37 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 10 0 0 10 0 10 10 0 10 0 0 10 10 0 % R
% Ser: 10 64 73 46 37 0 19 46 46 19 55 55 55 46 10 % S
% Thr: 0 10 0 10 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 19 0 0 0 0 0 0 0 10 0 0 19 10 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _