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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRPC1
All Species:
21.52
Human Site:
S222
Identified Species:
47.33
UniProt:
P48995
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48995
NP_003295.1
793
91212
S222
D
I
Y
R
C
L
A
S
P
A
L
I
M
L
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112011
792
91106
S221
D
I
Y
R
C
L
A
S
P
A
L
I
M
L
T
Dog
Lupus familis
XP_542818
793
91218
S222
D
I
Y
R
C
L
A
S
P
A
L
I
M
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61056
809
92709
S238
D
I
Y
R
C
L
A
S
P
A
L
I
M
L
T
Rat
Rattus norvegicus
Q9QX01
759
87599
F220
L
S
L
V
E
V
E
F
W
N
D
Y
E
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505454
837
95954
S266
D
I
Y
R
C
L
A
S
P
A
L
I
M
L
T
Chicken
Gallus gallus
NP_001004409
781
90059
L216
A
S
P
A
L
I
M
L
T
E
E
D
P
I
L
Frog
Xenopus laevis
NP_001083819
778
90015
E215
P
A
L
I
M
L
T
E
E
D
P
I
L
R
A
Zebra Danio
Brachydanio rerio
XP_699455
749
86999
E211
E
F
R
N
D
Y
E
E
L
A
K
Q
C
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJJ7
1128
127091
E216
T
A
F
E
L
S
W
E
L
R
R
L
S
F
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34586
1027
118084
S227
N
T
F
R
A
L
A
S
P
A
W
M
S
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
99.6
N.A.
97.7
94.8
N.A.
88.5
92.4
87.7
79.8
N.A.
28.5
N.A.
28.7
N.A.
Protein Similarity:
100
N.A.
99.8
99.7
N.A.
97.9
95.4
N.A.
92.8
96.8
94.3
88.4
N.A.
45.4
N.A.
46.7
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
0
N.A.
100
0
13.3
6.6
N.A.
0
N.A.
53.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
6.6
N.A.
100
13.3
20
13.3
N.A.
13.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
10
10
0
55
0
0
64
0
0
0
0
10
% A
% Cys:
0
0
0
0
46
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
46
0
0
0
10
0
0
0
0
10
10
10
0
0
0
% D
% Glu:
10
0
0
10
10
0
19
28
10
10
10
0
10
10
0
% E
% Phe:
0
10
19
0
0
0
0
10
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
46
0
10
0
10
0
0
0
0
0
55
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% K
% Leu:
10
0
19
0
19
64
0
10
19
0
46
10
10
55
28
% L
% Met:
0
0
0
0
10
0
10
0
0
0
0
10
46
0
10
% M
% Asn:
10
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
10
0
10
0
0
0
0
0
55
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
10
55
0
0
0
0
0
10
10
0
0
10
0
% R
% Ser:
0
19
0
0
0
10
0
55
0
0
0
0
19
0
0
% S
% Thr:
10
10
0
0
0
0
10
0
10
0
0
0
0
0
55
% T
% Val:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
10
0
10
0
0
0
0
% W
% Tyr:
0
0
46
0
0
10
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _