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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLD2
All Species:
24.24
Human Site:
S124
Identified Species:
35.56
UniProt:
P49005
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49005
NP_001120690.1
469
51289
S124
L
L
P
Q
P
P
R
S
K
Y
I
H
P
D
D
Chimpanzee
Pan troglodytes
XP_528027
455
49608
E114
I
L
R
E
I
S
E
E
H
N
L
L
P
Q
P
Rhesus Macaque
Macaca mulatta
XP_001093710
469
51277
S124
L
L
P
Q
P
P
R
S
K
Y
I
H
P
D
D
Dog
Lupus familis
XP_539802
469
51364
S124
L
L
P
Q
P
P
R
S
K
Y
I
H
P
D
D
Cat
Felis silvestris
Mouse
Mus musculus
O35654
469
51350
S124
L
V
P
Q
P
P
R
S
K
Y
I
H
P
D
D
Rat
Rattus norvegicus
Q6AXY4
469
51328
S124
L
I
P
Q
P
P
R
S
K
Y
I
H
P
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520117
471
51420
T124
L
L
P
Q
P
T
R
T
K
Y
L
H
P
D
D
Chicken
Gallus gallus
Frog
Xenopus laevis
O93610
463
50629
Q124
L
L
P
Q
P
A
R
Q
K
Y
I
S
D
S
D
Zebra Danio
Brachydanio rerio
NP_998468
467
51808
A122
L
L
P
Q
P
P
R
A
K
Y
I
S
Q
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W088
431
47990
R102
Q
L
A
P
Q
P
P
R
Q
N
Y
S
D
P
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19366
451
50385
Y118
E
E
D
E
V
K
R
Y
A
G
S
I
E
D
R
Sea Urchin
Strong. purpuratus
XP_782368
442
49455
D113
V
R
E
R
F
F
S
D
S
D
F
L
V
L
E
Poplar Tree
Populus trichocarpa
XP_002309305
442
49175
F113
P
L
V
K
P
H
N
F
M
H
P
D
D
H
L
Maize
Zea mays
NP_001168398
435
48508
H106
A
I
P
L
V
K
P
H
N
F
M
H
P
D
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48520
456
51321
H119
V
T
P
L
V
K
P
H
N
F
M
H
P
D
D
Baker's Yeast
Sacchar. cerevisiae
P46957
487
55277
S135
G
A
P
D
L
T
K
S
Y
T
D
K
E
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
98.9
93.1
N.A.
94.2
94
N.A.
85.3
N.A.
68.8
66.5
N.A.
40
N.A.
28.3
50.5
Protein Similarity:
100
97
99.5
96.5
N.A.
97
96.8
N.A.
90.8
N.A.
79
79.7
N.A.
56.5
N.A.
50.1
66.3
P-Site Identity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
80
N.A.
66.6
73.3
N.A.
13.3
N.A.
13.3
0
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
93.3
N.A.
66.6
80
N.A.
26.6
N.A.
20
20
Percent
Protein Identity:
41.5
38.8
N.A.
39.6
25.4
N.A.
Protein Similarity:
56.9
56.9
N.A.
57.1
48
N.A.
P-Site Identity:
13.3
33.3
N.A.
33.3
13.3
N.A.
P-Site Similarity:
26.6
53.3
N.A.
53.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
0
7
0
7
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
0
0
0
7
0
7
7
7
19
57
63
% D
% Glu:
7
7
7
13
0
0
7
7
0
0
0
0
13
0
13
% E
% Phe:
0
0
0
0
7
7
0
7
0
13
7
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
7
0
0
0
7
7
% G
% His:
0
0
0
0
0
7
0
13
7
7
0
50
0
7
0
% H
% Ile:
7
13
0
0
7
0
0
0
0
0
44
7
0
0
0
% I
% Lys:
0
0
0
7
0
19
7
0
50
0
0
7
0
0
0
% K
% Leu:
50
57
0
13
7
0
0
0
0
0
13
13
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
7
0
13
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
13
13
0
0
0
0
0
% N
% Pro:
7
0
69
7
57
44
19
0
0
0
7
0
57
7
7
% P
% Gln:
7
0
0
50
7
0
0
7
7
0
0
0
7
7
0
% Q
% Arg:
0
7
7
7
0
0
57
7
0
0
0
0
0
0
7
% R
% Ser:
0
0
0
0
0
7
7
38
7
0
7
19
0
13
0
% S
% Thr:
0
7
0
0
0
13
0
7
0
7
0
0
0
0
0
% T
% Val:
13
7
7
0
19
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
7
50
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _