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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLD2
All Species:
20.91
Human Site:
S15
Identified Species:
30.67
UniProt:
P49005
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49005
NP_001120690.1
469
51289
S15
Q
R
A
H
T
L
L
S
P
P
S
A
N
N
A
Chimpanzee
Pan troglodytes
XP_528027
455
49608
S15
Q
R
A
H
T
L
L
S
P
P
S
A
N
N
A
Rhesus Macaque
Macaca mulatta
XP_001093710
469
51277
S15
Q
R
T
H
T
L
L
S
P
P
S
A
N
N
A
Dog
Lupus familis
XP_539802
469
51364
S15
Q
R
A
H
T
L
L
S
P
P
S
A
S
N
A
Cat
Felis silvestris
Mouse
Mus musculus
O35654
469
51350
A15
Q
R
A
H
T
L
L
A
P
P
S
A
S
N
A
Rat
Rattus norvegicus
Q6AXY4
469
51328
S15
Q
R
A
H
T
L
L
S
P
P
S
A
S
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520117
471
51420
A15
Q
R
A
G
T
L
L
A
P
P
S
T
K
S
S
Chicken
Gallus gallus
Frog
Xenopus laevis
O93610
463
50629
T15
S
G
G
P
G
L
L
T
A
P
S
E
V
Q
S
Zebra Danio
Brachydanio rerio
NP_998468
467
51808
A15
P
K
E
T
L
L
A
A
P
G
S
E
E
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W088
431
47990
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19366
451
50385
Y18
Y
K
N
V
S
D
R
Y
I
L
T
E
K
D
K
Sea Urchin
Strong. purpuratus
XP_782368
442
49455
C14
E
T
F
Q
R
L
S
C
D
Y
E
N
L
S
S
Poplar Tree
Populus trichocarpa
XP_002309305
442
49175
R14
D
I
E
K
N
I
Q
R
K
R
S
T
Y
Q
S
Maize
Zea mays
NP_001168398
435
48508
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48520
456
51321
N17
E
R
K
Q
S
D
Y
N
S
L
V
R
T
L
L
Baker's Yeast
Sacchar. cerevisiae
P46957
487
55277
N18
D
R
S
L
Q
D
E
N
L
S
Q
P
R
T
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
98.9
93.1
N.A.
94.2
94
N.A.
85.3
N.A.
68.8
66.5
N.A.
40
N.A.
28.3
50.5
Protein Similarity:
100
97
99.5
96.5
N.A.
97
96.8
N.A.
90.8
N.A.
79
79.7
N.A.
56.5
N.A.
50.1
66.3
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
93.3
N.A.
60
N.A.
26.6
20
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
80
N.A.
40
33.3
N.A.
0
N.A.
26.6
26.6
Percent
Protein Identity:
41.5
38.8
N.A.
39.6
25.4
N.A.
Protein Similarity:
56.9
56.9
N.A.
57.1
48
N.A.
P-Site Identity:
6.6
0
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
0
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
38
0
0
0
7
19
7
0
0
38
0
0
38
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
19
0
0
7
0
0
0
0
7
0
% D
% Glu:
13
0
13
0
0
0
7
0
0
0
7
19
7
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
7
7
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
38
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
7
0
0
7
0
0
0
0
0
0
% I
% Lys:
0
13
7
7
0
0
0
0
7
0
0
0
13
0
7
% K
% Leu:
0
0
0
7
7
63
50
0
7
13
0
0
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
7
0
0
13
0
0
0
7
19
38
0
% N
% Pro:
7
0
0
7
0
0
0
0
50
50
0
7
0
7
0
% P
% Gln:
44
0
0
13
7
0
7
0
0
0
7
0
0
13
0
% Q
% Arg:
0
57
0
0
7
0
7
7
0
7
0
7
7
0
7
% R
% Ser:
7
0
7
0
13
0
7
32
7
7
63
0
19
13
25
% S
% Thr:
0
7
7
7
44
0
0
7
0
0
7
13
7
7
0
% T
% Val:
0
0
0
7
0
0
0
0
0
0
7
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
7
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _