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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLD2
All Species:
30
Human Site:
S249
Identified Species:
44
UniProt:
P49005
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49005
NP_001120690.1
469
51289
S249
I
L
A
G
N
L
L
S
H
S
T
Q
S
R
D
Chimpanzee
Pan troglodytes
XP_528027
455
49608
A235
D
E
G
E
Q
C
S
A
A
H
V
S
R
V
I
Rhesus Macaque
Macaca mulatta
XP_001093710
469
51277
S249
I
L
A
G
N
L
L
S
H
S
T
Q
S
R
D
Dog
Lupus familis
XP_539802
469
51364
S249
I
L
A
G
N
L
L
S
H
N
T
Q
S
R
D
Cat
Felis silvestris
Mouse
Mus musculus
O35654
469
51350
S249
I
L
A
G
N
L
L
S
H
N
T
Q
S
R
D
Rat
Rattus norvegicus
Q6AXY4
469
51328
S249
I
L
A
G
N
L
L
S
H
N
T
Q
S
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520117
471
51420
S249
I
L
A
G
N
L
L
S
Q
I
T
Q
N
R
D
Chicken
Gallus gallus
Frog
Xenopus laevis
O93610
463
50629
S249
I
L
A
G
N
L
L
S
E
N
T
Q
G
K
D
Zebra Danio
Brachydanio rerio
NP_998468
467
51808
S247
I
L
A
G
N
L
L
S
R
S
T
Q
D
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W088
431
47990
G220
M
V
R
L
I
V
A
G
N
S
V
R
A
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19366
451
50385
E239
V
V
I
G
P
L
V
E
T
K
S
N
G
C
D
Sea Urchin
Strong. purpuratus
XP_782368
442
49455
L231
V
I
I
A
G
N
S
L
S
E
S
T
Q
D
K
Poplar Tree
Populus trichocarpa
XP_002309305
442
49175
F231
A
E
I
V
H
V
V
F
A
G
N
S
V
E
I
Maize
Zea mays
NP_001168398
435
48508
V224
S
N
I
V
R
I
V
V
V
G
N
S
V
H
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48520
456
51321
E245
V
I
A
G
N
S
F
E
F
P
R
K
L
I
N
Baker's Yeast
Sacchar. cerevisiae
P46957
487
55277
D267
C
G
N
S
V
D
F
D
I
K
S
V
N
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
98.9
93.1
N.A.
94.2
94
N.A.
85.3
N.A.
68.8
66.5
N.A.
40
N.A.
28.3
50.5
Protein Similarity:
100
97
99.5
96.5
N.A.
97
96.8
N.A.
90.8
N.A.
79
79.7
N.A.
56.5
N.A.
50.1
66.3
P-Site Identity:
100
0
100
93.3
N.A.
93.3
93.3
N.A.
80
N.A.
73.3
80
N.A.
6.6
N.A.
20
0
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
86.6
N.A.
86.6
86.6
N.A.
46.6
N.A.
46.6
20
Percent
Protein Identity:
41.5
38.8
N.A.
39.6
25.4
N.A.
Protein Similarity:
56.9
56.9
N.A.
57.1
48
N.A.
P-Site Identity:
0
0
N.A.
20
6.6
N.A.
P-Site Similarity:
20
13.3
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
57
7
0
0
7
7
13
0
0
0
7
0
7
% A
% Cys:
7
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
0
0
0
0
7
0
7
0
0
0
0
7
7
63
% D
% Glu:
0
13
0
7
0
0
0
13
7
7
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
13
7
7
0
0
0
0
0
0
% F
% Gly:
0
7
7
63
7
0
0
7
0
13
0
0
13
0
0
% G
% His:
0
0
0
0
7
0
0
0
32
7
0
0
0
7
0
% H
% Ile:
50
13
25
0
7
7
0
0
7
7
0
0
0
7
19
% I
% Lys:
0
0
0
0
0
0
0
0
0
13
0
7
0
19
7
% K
% Leu:
0
50
0
7
0
57
50
7
0
0
0
0
7
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
57
7
0
0
7
25
13
7
13
0
7
% N
% Pro:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
7
0
0
50
7
0
0
% Q
% Arg:
0
0
7
0
7
0
0
0
7
0
7
7
7
38
0
% R
% Ser:
7
0
0
7
0
7
13
50
7
25
19
19
32
7
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
50
7
0
0
0
% T
% Val:
19
13
0
13
7
13
19
7
7
0
13
7
13
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _