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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLD2
All Species:
35.45
Human Site:
S272
Identified Species:
52
UniProt:
P49005
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49005
NP_001120690.1
469
51289
S272
T
K
K
T
Q
A
A
S
V
E
A
V
K
M
L
Chimpanzee
Pan troglodytes
XP_528027
455
49608
I258
S
T
Q
S
R
D
S
I
N
K
A
K
Y
L
T
Rhesus Macaque
Macaca mulatta
XP_001093710
469
51277
S272
T
K
K
T
Q
A
A
S
V
E
A
V
K
M
L
Dog
Lupus familis
XP_539802
469
51364
S272
T
K
K
T
Q
A
A
S
V
E
A
V
K
M
L
Cat
Felis silvestris
Mouse
Mus musculus
O35654
469
51350
S272
T
K
K
T
Q
A
A
S
V
E
A
V
K
M
L
Rat
Rattus norvegicus
Q6AXY4
469
51328
S272
T
K
K
T
Q
A
A
S
V
E
A
V
K
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520117
471
51420
S272
T
K
K
A
Q
A
A
S
V
E
A
I
K
M
L
Chicken
Gallus gallus
Frog
Xenopus laevis
O93610
463
50629
S272
S
K
K
T
Q
A
A
S
V
E
A
V
K
M
L
Zebra Danio
Brachydanio rerio
NP_998468
467
51808
S270
T
K
K
T
Q
A
G
S
V
E
A
I
R
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W088
431
47990
A243
V
A
R
T
Q
A
N
A
N
D
T
V
Q
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19366
451
50385
H262
T
L
S
R
A
E
K
H
S
S
T
A
S
L
I
Sea Urchin
Strong. purpuratus
XP_782368
442
49455
G254
L
T
R
K
S
Q
A
G
T
V
E
G
V
K
T
Poplar Tree
Populus trichocarpa
XP_002309305
442
49175
S254
N
L
A
S
K
D
Q
S
R
L
S
E
P
V
Q
Maize
Zea mays
NP_001168398
435
48508
S247
T
V
P
S
K
D
Q
S
R
I
A
E
P
I
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48520
456
51321
T268
L
A
S
K
D
Q
S
T
L
Y
E
P
I
K
E
Baker's Yeast
Sacchar. cerevisiae
P46957
487
55277
I290
F
S
K
F
L
H
N
I
L
P
S
I
S
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
98.9
93.1
N.A.
94.2
94
N.A.
85.3
N.A.
68.8
66.5
N.A.
40
N.A.
28.3
50.5
Protein Similarity:
100
97
99.5
96.5
N.A.
97
96.8
N.A.
90.8
N.A.
79
79.7
N.A.
56.5
N.A.
50.1
66.3
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
86.6
N.A.
93.3
73.3
N.A.
26.6
N.A.
6.6
6.6
P-Site Similarity:
100
53.3
100
100
N.A.
100
100
N.A.
93.3
N.A.
100
93.3
N.A.
60
N.A.
20
13.3
Percent
Protein Identity:
41.5
38.8
N.A.
39.6
25.4
N.A.
Protein Similarity:
56.9
56.9
N.A.
57.1
48
N.A.
P-Site Identity:
6.6
20
N.A.
0
6.6
N.A.
P-Site Similarity:
33.3
40
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
7
7
7
57
50
7
0
0
63
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
19
0
0
0
7
0
0
0
0
7
% D
% Glu:
0
0
0
0
0
7
0
0
0
50
13
13
0
0
7
% E
% Phe:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
7
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
7
0
19
7
7
7
% I
% Lys:
0
50
57
13
13
0
7
0
0
7
0
7
44
13
7
% K
% Leu:
13
13
0
0
7
0
0
0
13
7
0
0
0
19
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
44
0
% M
% Asn:
7
0
0
0
0
0
13
0
13
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
7
0
7
13
0
0
% P
% Gln:
0
0
7
0
57
13
13
0
0
0
0
0
7
0
7
% Q
% Arg:
0
0
13
7
7
0
0
0
13
0
0
0
7
0
0
% R
% Ser:
13
7
13
19
7
0
13
63
7
7
13
0
13
0
0
% S
% Thr:
57
13
0
50
0
0
0
7
7
0
13
0
0
0
13
% T
% Val:
7
7
0
0
0
0
0
0
50
7
0
44
7
13
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _