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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLD2 All Species: 28.79
Human Site: T23 Identified Species: 42.22
UniProt: P49005 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49005 NP_001120690.1 469 51289 T23 P P S A N N A T F A R V P V A
Chimpanzee Pan troglodytes XP_528027 455 49608 T23 P P S A N N A T F A R V P V A
Rhesus Macaque Macaca mulatta XP_001093710 469 51277 T23 P P S A N N A T F A R V P V A
Dog Lupus familis XP_539802 469 51364 T23 P P S A S N A T F A R V P V S
Cat Felis silvestris
Mouse Mus musculus O35654 469 51350 T23 P P S A S N A T F A R V P V A
Rat Rattus norvegicus Q6AXY4 469 51328 T23 P P S A S N A T F A R V P V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520117 471 51420 T23 P P S T K S S T F A R E P V T
Chicken Gallus gallus
Frog Xenopus laevis O93610 463 50629 T23 A P S E V Q S T F T R V S N T
Zebra Danio Brachydanio rerio NP_998468 467 51808 F23 P G S E E P V F E R A E P A Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W088 431 47990 N11 R L E T K Y E N L S S I F R L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19366 451 50385 K26 I L T E K D K K G A F T R Q Y
Sea Urchin Strong. purpuratus XP_782368 442 49455 R22 D Y E N L S S R F K L Q D R N
Poplar Tree Populus trichocarpa XP_002309305 442 49175 L22 K R S T Y Q S L D E T F D I Q
Maize Zea mays NP_001168398 435 48508 S15 E R K Q A A Y S N L D E R Y A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O48520 456 51321 L25 S L V R T L L L Y R L V Q D E
Baker's Yeast Sacchar. cerevisiae P46957 487 55277 V26 L S Q P R T R V R I V D D N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 98.9 93.1 N.A. 94.2 94 N.A. 85.3 N.A. 68.8 66.5 N.A. 40 N.A. 28.3 50.5
Protein Similarity: 100 97 99.5 96.5 N.A. 97 96.8 N.A. 90.8 N.A. 79 79.7 N.A. 56.5 N.A. 50.1 66.3
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 60 N.A. 40 20 N.A. 0 N.A. 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 73.3 N.A. 46.6 20 N.A. 13.3 N.A. 20 20
Percent
Protein Identity: 41.5 38.8 N.A. 39.6 25.4 N.A.
Protein Similarity: 56.9 56.9 N.A. 57.1 48 N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 0 N.A.
P-Site Similarity: 20 13.3 N.A. 13.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 38 7 7 38 0 0 50 7 0 0 7 38 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 7 0 0 7 0 7 7 19 7 0 % D
% Glu: 7 0 13 19 7 0 7 0 7 7 0 19 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 7 57 0 7 7 7 0 0 % F
% Gly: 0 7 0 0 0 0 0 0 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 7 0 7 0 7 0 % I
% Lys: 7 0 7 0 19 0 7 7 0 7 0 0 0 0 0 % K
% Leu: 7 19 0 0 7 7 7 13 7 7 13 0 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 19 38 0 7 7 0 0 0 0 13 7 % N
% Pro: 50 50 0 7 0 7 0 0 0 0 0 0 50 0 0 % P
% Gln: 0 0 7 7 0 13 0 0 0 0 0 7 7 7 7 % Q
% Arg: 7 13 0 7 7 0 7 7 7 13 50 0 13 13 0 % R
% Ser: 7 7 63 0 19 13 25 7 0 7 7 0 7 0 7 % S
% Thr: 0 0 7 19 7 7 0 50 0 7 7 7 0 0 13 % T
% Val: 0 0 7 0 7 0 7 7 0 0 7 50 0 44 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 7 7 0 7 0 0 0 0 7 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _