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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PXN All Species: 10.61
Human Site: S302 Identified Species: 19.44
UniProt: P49023 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49023 NP_001074324.1 591 64533 S302 W P R D G G R S S P G G Q D E
Chimpanzee Pan troglodytes XP_001159942 589 64154 S300 W P R D G G R S S P G G Q D E
Rhesus Macaque Macaca mulatta XP_001085795 563 61555 P295 G K T G S S S P P G G P P K P
Dog Lupus familis XP_543425 664 72715 R375 I T V Q P R G R R A G G Q L V
Cat Felis silvestris
Mouse Mus musculus Q8VI36 591 64458 S302 W P P S S R Q S S P E G Q D E
Rat Rattus norvegicus Q66H76 586 64001 E297 S A T R E L D E L M A S L S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P49024 559 61224 S290 G K A G G S S S P P S T T P K
Frog Xenopus laevis Q2TCH4 506 55983 D250 S V P R S D L D S M L V K L Q
Zebra Danio Brachydanio rerio Q6P7E4 419 45574 K163 C P V T V K S K P A D K H D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523601 581 64668 T292 T V Q H Q T V T D Y A R P N K
Honey Bee Apis mellifera XP_624308 559 62451 E274 Q T R I H I T E T H T T H H Y
Nematode Worm Caenorhab. elegans Q09476 413 46434 T157 H S D S M I G T M N G E L S S
Sea Urchin Strong. purpuratus XP_780574 695 76058 P406 P A Q H P A P P A Q Q Y P P Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 92.5 83.1 N.A. 93.7 74.9 N.A. N.A. 84.7 41.2 21.6 N.A. 43.1 43.3 33.8 43.4
Protein Similarity: 100 99.1 92.8 85.2 N.A. 95.7 78.3 N.A. N.A. 88.4 54.3 36.5 N.A. 54.8 57 47 56.2
P-Site Identity: 100 100 6.6 20 N.A. 60 0 N.A. N.A. 20 6.6 13.3 N.A. 0 6.6 6.6 0
P-Site Similarity: 100 100 6.6 20 N.A. 66.6 6.6 N.A. N.A. 26.6 20 13.3 N.A. 26.6 13.3 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 8 0 0 8 0 0 8 16 16 0 0 0 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 16 0 8 8 8 8 0 8 0 0 31 8 % D
% Glu: 0 0 0 0 8 0 0 16 0 0 8 8 0 0 24 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 0 0 16 24 16 16 0 0 8 39 31 0 0 0 % G
% His: 8 0 0 16 8 0 0 0 0 8 0 0 16 8 0 % H
% Ile: 8 0 0 8 0 16 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 16 0 0 0 8 0 8 0 0 0 8 8 8 16 % K
% Leu: 0 0 0 0 0 8 8 0 8 0 8 0 16 16 0 % L
% Met: 0 0 0 0 8 0 0 0 8 16 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % N
% Pro: 8 31 16 0 16 0 8 16 24 31 0 8 24 16 8 % P
% Gln: 8 0 16 8 8 0 8 0 0 8 8 0 31 0 16 % Q
% Arg: 0 0 24 16 0 16 16 8 8 0 0 8 0 0 0 % R
% Ser: 16 8 0 16 24 16 24 31 31 0 8 8 0 16 8 % S
% Thr: 8 16 16 8 0 8 8 16 8 0 8 16 8 0 0 % T
% Val: 0 16 16 0 8 0 8 0 0 0 0 8 0 0 8 % V
% Trp: 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _