Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PXN All Species: 19.7
Human Site: S85 Identified Species: 36.11
UniProt: P49023 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49023 NP_001074324.1 591 64533 S85 H Q Q P Q S S S P V Y G S S A
Chimpanzee Pan troglodytes XP_001159942 589 64154 S83 H Q Q P Q S S S P V Y G S S A
Rhesus Macaque Macaca mulatta XP_001085795 563 61555 S91 H Q Q P Q S S S P V Y G S S A
Dog Lupus familis XP_543425 664 72715 S96 H Q Q P Q P P S P V Y S S S T
Cat Felis silvestris
Mouse Mus musculus Q8VI36 591 64458 L85 H Q Q P P S P L P V Y S S S A
Rat Rattus norvegicus Q66H76 586 64001 S85 H Q Q P P S P S P I Y S S S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P49024 559 61224 S85 H Q Q P Q S Q S P I Y S S S A
Frog Xenopus laevis Q2TCH4 506 55983 V60 S D H E T F P V D K D H L Y S
Zebra Danio Brachydanio rerio Q6P7E4 419 45574
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523601 581 64668 P81 S L R G K A Q P Q V Y Q E H Y
Honey Bee Apis mellifera XP_624308 559 62451 N83 K M P S L N N N L S E L D T L
Nematode Worm Caenorhab. elegans Q09476 413 46434
Sea Urchin Strong. purpuratus XP_780574 695 76058 Q85 S E P L Y Q V Q D I H L P P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 92.5 83.1 N.A. 93.7 74.9 N.A. N.A. 84.7 41.2 21.6 N.A. 43.1 43.3 33.8 43.4
Protein Similarity: 100 99.1 92.8 85.2 N.A. 95.7 78.3 N.A. N.A. 88.4 54.3 36.5 N.A. 54.8 57 47 56.2
P-Site Identity: 100 100 100 73.3 N.A. 73.3 66.6 N.A. N.A. 80 0 0 N.A. 13.3 0 0 0
P-Site Similarity: 100 100 100 73.3 N.A. 73.3 73.3 N.A. N.A. 86.6 6.6 0 N.A. 33.3 26.6 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 39 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 16 0 8 0 8 0 0 % D
% Glu: 0 8 0 8 0 0 0 0 0 0 8 0 8 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 0 0 24 0 0 0 % G
% His: 54 0 8 0 0 0 0 0 0 0 8 8 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 24 0 0 0 0 0 % I
% Lys: 8 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 0 8 0 8 8 0 0 8 8 0 0 16 8 0 8 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 8 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 16 54 16 8 31 8 54 0 0 0 8 8 0 % P
% Gln: 0 54 54 0 39 8 16 8 8 0 0 8 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 24 0 0 8 0 47 24 47 0 8 0 31 54 54 16 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 16 % T
% Val: 0 0 0 0 0 0 8 8 0 47 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 62 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _