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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PXN All Species: 21.52
Human Site: S90 Identified Species: 39.44
UniProt: P49023 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49023 NP_001074324.1 591 64533 S90 S S S P V Y G S S A K T S S V
Chimpanzee Pan troglodytes XP_001159942 589 64154 S88 S S S P V Y G S S A K T S S V
Rhesus Macaque Macaca mulatta XP_001085795 563 61555 S96 S S S P V Y G S S A K T S S A
Dog Lupus familis XP_543425 664 72715 S101 P P S P V Y S S S T K T S S A
Cat Felis silvestris
Mouse Mus musculus Q8VI36 591 64458 S90 S P L P V Y S S S A K N S S A
Rat Rattus norvegicus Q66H76 586 64001 S90 S P S P I Y S S S T K N S S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P49024 559 61224 S90 S Q S P I Y S S S A K S S S A
Frog Xenopus laevis Q2TCH4 506 55983 L65 F P V D K D H L Y S T V Q K Y
Zebra Danio Brachydanio rerio Q6P7E4 419 45574
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523601 581 64668 E86 A Q P Q V Y Q E H Y S V E T R
Honey Bee Apis mellifera XP_624308 559 62451 D88 N N N L S E L D T L L Q D L S
Nematode Worm Caenorhab. elegans Q09476 413 46434
Sea Urchin Strong. purpuratus XP_780574 695 76058 P90 Q V Q D I H L P P S A R V Y A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 92.5 83.1 N.A. 93.7 74.9 N.A. N.A. 84.7 41.2 21.6 N.A. 43.1 43.3 33.8 43.4
Protein Similarity: 100 99.1 92.8 85.2 N.A. 95.7 78.3 N.A. N.A. 88.4 54.3 36.5 N.A. 54.8 57 47 56.2
P-Site Identity: 100 100 93.3 66.6 N.A. 66.6 60 N.A. N.A. 66.6 0 0 N.A. 13.3 0 0 0
P-Site Similarity: 100 100 93.3 66.6 N.A. 66.6 66.6 N.A. N.A. 80 6.6 0 N.A. 26.6 26.6 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 39 8 0 0 0 47 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 16 0 8 0 8 0 0 0 0 8 0 0 % D
% Glu: 0 0 0 0 0 8 0 8 0 0 0 0 8 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 24 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 8 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 24 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 0 0 0 0 54 0 0 8 0 % K
% Leu: 0 0 8 8 0 0 16 8 0 8 8 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 8 0 0 0 0 0 0 0 0 16 0 0 0 % N
% Pro: 8 31 8 54 0 0 0 8 8 0 0 0 0 0 0 % P
% Gln: 8 16 8 8 0 0 8 0 0 0 0 8 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % R
% Ser: 47 24 47 0 8 0 31 54 54 16 8 8 54 54 8 % S
% Thr: 0 0 0 0 0 0 0 0 8 16 8 31 0 8 0 % T
% Val: 0 8 8 0 47 0 0 0 0 0 0 16 8 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 62 0 0 8 8 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _