KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXN
All Species:
40
Human Site:
T543
Identified Species:
73.33
UniProt:
P49023
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49023
NP_001074324.1
591
64533
T543
S
G
C
Q
K
P
I
T
G
R
C
I
T
A
M
Chimpanzee
Pan troglodytes
XP_001159942
589
64154
T541
S
G
C
Q
K
P
I
T
G
R
C
I
T
A
M
Rhesus Macaque
Macaca mulatta
XP_001085795
563
61555
T515
S
G
C
Q
K
P
I
T
G
R
C
I
T
A
M
Dog
Lupus familis
XP_543425
664
72715
T616
S
G
C
Q
K
P
I
T
G
R
C
I
T
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI36
591
64458
T543
S
G
C
Q
K
P
I
T
G
R
C
I
T
A
M
Rat
Rattus norvegicus
Q66H76
586
64001
T538
S
G
C
Q
K
P
I
T
G
R
C
I
T
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49024
559
61224
T511
S
G
C
Q
K
P
I
T
G
R
C
I
T
A
M
Frog
Xenopus laevis
Q2TCH4
506
55983
H470
T
A
M
G
K
K
F
H
P
Q
H
L
N
C
T
Zebra Danio
Brachydanio rerio
Q6P7E4
419
45574
W383
L
E
A
L
G
Y
S
W
H
D
T
C
F
V
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523601
581
64668
T533
A
G
C
S
K
P
I
T
G
R
C
I
T
A
M
Honey Bee
Apis mellifera
XP_624308
559
62451
T511
A
G
C
H
K
P
I
T
G
R
C
I
T
A
M
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
F377
R
K
F
H
P
E
H
F
R
C
S
Y
C
N
H
Sea Urchin
Strong. purpuratus
XP_780574
695
76058
T647
A
G
C
N
K
P
I
T
G
R
C
I
T
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.5
83.1
N.A.
93.7
74.9
N.A.
N.A.
84.7
41.2
21.6
N.A.
43.1
43.3
33.8
43.4
Protein Similarity:
100
99.1
92.8
85.2
N.A.
95.7
78.3
N.A.
N.A.
88.4
54.3
36.5
N.A.
54.8
57
47
56.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
6.6
0
N.A.
86.6
86.6
0
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
26.6
0
N.A.
93.3
93.3
0
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
8
0
0
0
0
0
0
0
0
0
0
77
0
% A
% Cys:
0
0
77
0
0
0
0
0
0
8
77
8
8
8
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
8
8
0
0
0
0
8
0
0
% F
% Gly:
0
77
0
8
8
0
0
0
77
0
0
0
0
0
0
% G
% His:
0
0
0
16
0
0
8
8
8
0
8
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
77
0
0
0
0
77
0
0
0
% I
% Lys:
0
8
0
0
85
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
77
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
0
0
0
0
8
77
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
54
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
8
77
0
0
0
0
0
% R
% Ser:
54
0
0
8
0
0
8
0
0
0
8
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
77
0
0
8
0
77
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _