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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXN
All Species:
31.21
Human Site:
Y409
Identified Species:
57.22
UniProt:
P49023
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49023
NP_001074324.1
591
64533
Y409
Q
P
Y
C
E
K
D
Y
H
N
L
F
S
P
R
Chimpanzee
Pan troglodytes
XP_001159942
589
64154
Y407
Q
P
Y
C
E
K
D
Y
H
N
L
F
S
P
R
Rhesus Macaque
Macaca mulatta
XP_001085795
563
61555
D398
Y
C
N
G
P
I
L
D
K
V
V
T
A
L
D
Dog
Lupus familis
XP_543425
664
72715
Y482
Q
P
Y
C
E
K
D
Y
H
N
L
F
S
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI36
591
64458
Y409
Q
P
Y
C
E
K
D
Y
H
S
L
F
S
P
R
Rat
Rattus norvegicus
Q66H76
586
64001
Y404
Q
P
Y
C
E
K
D
Y
H
S
L
F
S
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49024
559
61224
D394
Y
C
N
G
P
I
L
D
K
V
V
T
A
L
D
Frog
Xenopus laevis
Q2TCH4
506
55983
P353
A
L
G
C
T
W
H
P
E
H
F
C
C
K
V
Zebra Danio
Brachydanio rerio
Q6P7E4
419
45574
E266
L
G
R
S
W
H
P
E
E
F
M
C
C
Q
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523601
581
64668
Y399
F
P
Y
C
E
P
D
Y
H
N
L
F
S
P
R
Honey Bee
Apis mellifera
XP_624308
559
62451
Y377
H
P
Y
C
E
P
D
Y
H
N
L
F
S
P
R
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
T260
N
F
H
I
E
C
F
T
C
A
E
C
N
Q
P
Sea Urchin
Strong. purpuratus
XP_780574
695
76058
Y513
Q
A
F
C
E
E
D
Y
H
N
L
F
A
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.5
83.1
N.A.
93.7
74.9
N.A.
N.A.
84.7
41.2
21.6
N.A.
43.1
43.3
33.8
43.4
Protein Similarity:
100
99.1
92.8
85.2
N.A.
95.7
78.3
N.A.
N.A.
88.4
54.3
36.5
N.A.
54.8
57
47
56.2
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
N.A.
0
6.6
0
N.A.
86.6
86.6
6.6
66.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
13.3
13.3
6.6
N.A.
86.6
86.6
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
0
8
0
0
24
0
0
% A
% Cys:
0
16
0
70
0
8
0
0
8
0
0
24
16
0
8
% C
% Asp:
0
0
0
0
0
0
62
16
0
0
0
0
0
0
16
% D
% Glu:
0
0
0
0
70
8
0
8
16
0
8
0
0
0
0
% E
% Phe:
8
8
8
0
0
0
8
0
0
8
8
62
0
0
0
% F
% Gly:
0
8
8
16
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
8
0
0
8
8
0
62
8
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
16
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
39
0
0
16
0
0
0
0
8
8
% K
% Leu:
8
8
0
0
0
0
16
0
0
0
62
0
0
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
16
0
0
0
0
0
0
47
0
0
8
0
0
% N
% Pro:
0
54
0
0
16
16
8
8
0
0
0
0
0
62
8
% P
% Gln:
47
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
54
% R
% Ser:
0
0
0
8
0
0
0
0
0
16
0
0
54
0
0
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
0
16
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
16
16
0
0
0
8
% V
% Trp:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
54
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _