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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR2C2 All Species: 24.24
Human Site: S330 Identified Species: 44.44
UniProt: P49116 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49116 NP_003289.2 596 65414 S330 T D S S S S P S L A D G I D T
Chimpanzee Pan troglodytes XP_001158452 596 65396 S330 T D S S S S P S L A D G I D T
Rhesus Macaque Macaca mulatta XP_001091445 632 69119 V365 A L G T L A N V V T S L A N L
Dog Lupus familis XP_541755 633 69174 S367 T D S S S P P S L A D G I D A
Cat Felis silvestris
Mouse Mus musculus P49117 596 65221 S330 T D S A S P P S L A D G I D A
Rat Rattus norvegicus P55094 596 65326 S330 T D S A S P P S L A D G I D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506287 596 65629 S330 M D G S S T P S L A D G M D P
Chicken Gallus gallus O42101 501 57084 S243 P Y T S S P E S I M G Y S Y M
Frog Xenopus laevis Q6GN21 637 70767 N371 D T L A K A L N Q S E N S T Q
Zebra Danio Brachydanio rerio Q06725 411 45463 P153 V Q R G R M P P T Q P N P G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16375 543 57969 M285 T Q P G L A G M H G Q Y Q I A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N4B8 615 68010 Y355 Q N P R N H Q Y I S E I T T R
Sea Urchin Strong. purpuratus Q26622 583 63834 T310 A L T K A L N T S G D S E A G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 86.2 93.2 N.A. 98.3 97.8 N.A. 94.1 24.3 57.9 29.8 N.A. 20.8 N.A. 21.1 51.3
Protein Similarity: 100 100 86.5 93.3 N.A. 98.8 98.8 N.A. 97.6 41.2 72.5 43.9 N.A. 37 N.A. 42.9 65.6
P-Site Identity: 100 100 0 86.6 N.A. 80 80 N.A. 66.6 20 0 6.6 N.A. 6.6 N.A. 0 6.6
P-Site Similarity: 100 100 26.6 86.6 N.A. 86.6 86.6 N.A. 80 33.3 33.3 6.6 N.A. 13.3 N.A. 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 24 8 24 0 0 0 47 0 0 8 8 31 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 47 0 0 0 0 0 0 0 0 54 0 0 47 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 16 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 16 16 0 0 8 0 0 16 8 47 0 8 8 % G
% His: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 16 0 0 8 39 8 0 % I
% Lys: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 16 8 0 16 8 8 0 47 0 0 8 0 0 8 % L
% Met: 8 0 0 0 0 8 0 8 0 8 0 0 8 0 8 % M
% Asn: 0 8 0 0 8 0 16 8 0 0 0 16 0 8 0 % N
% Pro: 8 0 16 0 0 31 54 8 0 0 8 0 8 0 8 % P
% Gln: 8 16 0 0 0 0 8 0 8 8 8 0 8 0 16 % Q
% Arg: 0 0 8 8 8 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 0 0 39 39 54 16 0 54 8 16 8 8 16 0 0 % S
% Thr: 47 8 16 8 0 8 0 8 8 8 0 0 8 16 16 % T
% Val: 8 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 8 0 0 0 16 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _